Effect of Resveratrol on Cultured Skin Fibroblasts from Patients with Oxidative Phosphorylation Defects

Few therapeutic options are available to patients with oxidative phosphorylation disorders. Administering pharmacological agents that are able to stimulate mitochondrial biogenesis have been put forward as a possible treatment, yet the approach remains in need of thorough testing. We investigated th...

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Veröffentlicht in:	Phytotherapy research 2014-02, Vol.28 (2), p.312-316
Hauptverfasser:	De Paepe, Boel, Vandemeulebroecke, Katrien, Smet, Joél, Vanlander, Arnaud, Seneca, Sara, Lissens, Willy, Van Hove, Johan LK, Deschepper, Ellen, Briones, Paz, Van Coster, Rudy
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured Citrate (si)-Synthase - metabolism Cytochrome-c Oxidase Deficiency - enzymology Cytochrome-c Oxidase Deficiency - physiopathology Electron Transport Complex II - deficiency Electron Transport Complex II - metabolism Electron Transport Complex IV - genetics Electron Transport Complex IV - metabolism Fibroblasts - drug effects Fibroblasts - enzymology Humans Mitochondria - drug effects Mitochondria - enzymology mitochondrial biogenesis oxidative phosphorylation Oxidative Phosphorylation - drug effects resveratrol Stilbenes - pharmacology
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