Rota virus Diarrhea in Hospitalized Children
To determine the frequency and clinical features of Rota virus diarrhea in children presenting in a tertiary care hospital. A cross-sectional, observational study. National Institute of Child Health, Karachi, from January to June 2007. A total of three hundred children of either gender aged 1 month...
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Veröffentlicht in: | Journal of the College of Physicians and Surgeons--Pakistan 2014-02, Vol.24 (2), p.114-117 |
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creator | Habib, Muhammad Irfan Kazi, Sayyeda Ghazala Ahmed Khan, Khalid Mehmood Zia, Nukhba |
description | To determine the frequency and clinical features of Rota virus diarrhea in children presenting in a tertiary care hospital.
A cross-sectional, observational study.
National Institute of Child Health, Karachi, from January to June 2007.
A total of three hundred children of either gender aged 1 month to 5 years, who presented with diarrhea of < 7 days as a primary illness were enrolled. Children with bloody diarrhea or nosocomial gastroenteritis acquired during hospitalization for other disease were not included. Detection of Rota virus in stool was done by enzyme linked immunoassay.
Out of 300 children, 188 (63%) tested positive and 112 (37%) tested negative for Rota virus. Positive Rota virus cases in 7 - 12 months of age was (n = 34, 18.08%). Overall, 151 (80.3%) children with Rota virus were less than 3 years old. 182 (60.7%) had fever, 118 (39.3%) had vomiting and 156 (82.9%) children had both fever and vomiting.
This study shows that Rota virus is a common organism causing diarrhea in children less than 3 years of age. There is a need to incorporate Rota virus vaccine in the national EPI program to decrease the disease burden as highlighted in this study. |
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A cross-sectional, observational study.
National Institute of Child Health, Karachi, from January to June 2007.
A total of three hundred children of either gender aged 1 month to 5 years, who presented with diarrhea of < 7 days as a primary illness were enrolled. Children with bloody diarrhea or nosocomial gastroenteritis acquired during hospitalization for other disease were not included. Detection of Rota virus in stool was done by enzyme linked immunoassay.
Out of 300 children, 188 (63%) tested positive and 112 (37%) tested negative for Rota virus. Positive Rota virus cases in 7 - 12 months of age was (n = 34, 18.08%). Overall, 151 (80.3%) children with Rota virus were less than 3 years old. 182 (60.7%) had fever, 118 (39.3%) had vomiting and 156 (82.9%) children had both fever and vomiting.
This study shows that Rota virus is a common organism causing diarrhea in children less than 3 years of age. There is a need to incorporate Rota virus vaccine in the national EPI program to decrease the disease burden as highlighted in this study.</description><identifier>ISSN: 1022-386X</identifier><identifier>EISSN: 1681-7168</identifier><identifier>PMID: 24491006</identifier><language>eng</language><publisher>Pakistan: College of Physicians and Surgeons Pakistan</publisher><subject>Causes of ; Child, Preschool ; Cross-Sectional Studies ; Demographic aspects ; Diarrhea - epidemiology ; Diarrhea - etiology ; Diarrhea - virology ; Diarrhea in children ; Distribution ; Enzyme Multiplied Immunoassay Technique ; Feces - virology ; Female ; Fever - complications ; Gastroenteritis - complications ; Gastroenteritis - epidemiology ; Gastroenteritis - virology ; Hospitalization ; Humans ; Infant ; Infant, Newborn ; Male ; Pakistan - epidemiology ; Population Surveillance ; Prevalence ; Rotavirus - isolation & purification ; Rotavirus - pathogenicity ; Rotavirus infections ; Rotavirus Infections - epidemiology ; Rotavirus Infections - virology ; Time Factors</subject><ispartof>Journal of the College of Physicians and Surgeons--Pakistan, 2014-02, Vol.24 (2), p.114-117</ispartof><rights>COPYRIGHT 2014 College of Physicians and Surgeons Pakistan</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24491006$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Habib, Muhammad Irfan</creatorcontrib><creatorcontrib>Kazi, Sayyeda Ghazala</creatorcontrib><creatorcontrib>Ahmed Khan, Khalid Mehmood</creatorcontrib><creatorcontrib>Zia, Nukhba</creatorcontrib><title>Rota virus Diarrhea in Hospitalized Children</title><title>Journal of the College of Physicians and Surgeons--Pakistan</title><addtitle>J Coll Physicians Surg Pak</addtitle><description>To determine the frequency and clinical features of Rota virus diarrhea in children presenting in a tertiary care hospital.
A cross-sectional, observational study.
National Institute of Child Health, Karachi, from January to June 2007.
A total of three hundred children of either gender aged 1 month to 5 years, who presented with diarrhea of < 7 days as a primary illness were enrolled. Children with bloody diarrhea or nosocomial gastroenteritis acquired during hospitalization for other disease were not included. Detection of Rota virus in stool was done by enzyme linked immunoassay.
Out of 300 children, 188 (63%) tested positive and 112 (37%) tested negative for Rota virus. Positive Rota virus cases in 7 - 12 months of age was (n = 34, 18.08%). Overall, 151 (80.3%) children with Rota virus were less than 3 years old. 182 (60.7%) had fever, 118 (39.3%) had vomiting and 156 (82.9%) children had both fever and vomiting.
This study shows that Rota virus is a common organism causing diarrhea in children less than 3 years of age. There is a need to incorporate Rota virus vaccine in the national EPI program to decrease the disease burden as highlighted in this study.</description><subject>Causes of</subject><subject>Child, Preschool</subject><subject>Cross-Sectional Studies</subject><subject>Demographic aspects</subject><subject>Diarrhea - epidemiology</subject><subject>Diarrhea - etiology</subject><subject>Diarrhea - virology</subject><subject>Diarrhea in children</subject><subject>Distribution</subject><subject>Enzyme Multiplied Immunoassay Technique</subject><subject>Feces - virology</subject><subject>Female</subject><subject>Fever - complications</subject><subject>Gastroenteritis - complications</subject><subject>Gastroenteritis - epidemiology</subject><subject>Gastroenteritis - virology</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Pakistan - epidemiology</subject><subject>Population Surveillance</subject><subject>Prevalence</subject><subject>Rotavirus - isolation & purification</subject><subject>Rotavirus - pathogenicity</subject><subject>Rotavirus infections</subject><subject>Rotavirus Infections - epidemiology</subject><subject>Rotavirus Infections - virology</subject><subject>Time Factors</subject><issn>1022-386X</issn><issn>1681-7168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkMlKA0EQhgdRTIy-ggx48eBI791zDHGJEBBEwdtQvUzSMkvsnhH06W1JPAhS8FdRfPVTVQfZFAuFC5n0MNWIkIIq8TrJTmJ8Q4hyrNRxNiGMlRghMc2unvoB8g8fxpjfeAhh4yD3Xb7s49YP0PgvZ_PFxjc2uO40O6qhie5sn2fZy93t82JZrB7vHxbzVbEmUg2FBQpa2BIcNpxjDqLklChLmTZagNISCQuMKquJkkiDAlsbwkuOTS2porPscue7Df376OJQtT4a1zTQuX6MFWZlidMlkiX0YoeuoXGV7-p-CGB-8GpOBRFIMlUm6vofKoV1rTd952qf-n8GzvcbjLp1ttoG30L4rH4fR78B7f5oGg</recordid><startdate>201402</startdate><enddate>201402</enddate><creator>Habib, Muhammad Irfan</creator><creator>Kazi, Sayyeda Ghazala</creator><creator>Ahmed Khan, Khalid Mehmood</creator><creator>Zia, Nukhba</creator><general>College of Physicians and Surgeons Pakistan</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201402</creationdate><title>Rota virus Diarrhea in Hospitalized Children</title><author>Habib, Muhammad Irfan ; Kazi, Sayyeda Ghazala ; Ahmed Khan, Khalid Mehmood ; Zia, Nukhba</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g278t-da3ab6d9ae1c5515a695328d34bcb6a8b706da438db2870ba8adfc25951cf7383</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Causes of</topic><topic>Child, Preschool</topic><topic>Cross-Sectional Studies</topic><topic>Demographic aspects</topic><topic>Diarrhea - epidemiology</topic><topic>Diarrhea - etiology</topic><topic>Diarrhea - virology</topic><topic>Diarrhea in children</topic><topic>Distribution</topic><topic>Enzyme Multiplied Immunoassay Technique</topic><topic>Feces - virology</topic><topic>Female</topic><topic>Fever - complications</topic><topic>Gastroenteritis - complications</topic><topic>Gastroenteritis - epidemiology</topic><topic>Gastroenteritis - virology</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Pakistan - epidemiology</topic><topic>Population Surveillance</topic><topic>Prevalence</topic><topic>Rotavirus - isolation & purification</topic><topic>Rotavirus - pathogenicity</topic><topic>Rotavirus infections</topic><topic>Rotavirus Infections - epidemiology</topic><topic>Rotavirus Infections - virology</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Habib, Muhammad Irfan</creatorcontrib><creatorcontrib>Kazi, Sayyeda Ghazala</creatorcontrib><creatorcontrib>Ahmed Khan, Khalid Mehmood</creatorcontrib><creatorcontrib>Zia, Nukhba</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the College of Physicians and Surgeons--Pakistan</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Habib, Muhammad Irfan</au><au>Kazi, Sayyeda Ghazala</au><au>Ahmed Khan, Khalid Mehmood</au><au>Zia, Nukhba</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rota virus Diarrhea in Hospitalized Children</atitle><jtitle>Journal of the College of Physicians and Surgeons--Pakistan</jtitle><addtitle>J Coll Physicians Surg Pak</addtitle><date>2014-02</date><risdate>2014</risdate><volume>24</volume><issue>2</issue><spage>114</spage><epage>117</epage><pages>114-117</pages><issn>1022-386X</issn><eissn>1681-7168</eissn><abstract>To determine the frequency and clinical features of Rota virus diarrhea in children presenting in a tertiary care hospital.
A cross-sectional, observational study.
National Institute of Child Health, Karachi, from January to June 2007.
A total of three hundred children of either gender aged 1 month to 5 years, who presented with diarrhea of < 7 days as a primary illness were enrolled. Children with bloody diarrhea or nosocomial gastroenteritis acquired during hospitalization for other disease were not included. Detection of Rota virus in stool was done by enzyme linked immunoassay.
Out of 300 children, 188 (63%) tested positive and 112 (37%) tested negative for Rota virus. Positive Rota virus cases in 7 - 12 months of age was (n = 34, 18.08%). Overall, 151 (80.3%) children with Rota virus were less than 3 years old. 182 (60.7%) had fever, 118 (39.3%) had vomiting and 156 (82.9%) children had both fever and vomiting.
This study shows that Rota virus is a common organism causing diarrhea in children less than 3 years of age. There is a need to incorporate Rota virus vaccine in the national EPI program to decrease the disease burden as highlighted in this study.</abstract><cop>Pakistan</cop><pub>College of Physicians and Surgeons Pakistan</pub><pmid>24491006</pmid><tpages>4</tpages></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
subjects | Causes of Child, Preschool Cross-Sectional Studies Demographic aspects Diarrhea - epidemiology Diarrhea - etiology Diarrhea - virology Diarrhea in children Distribution Enzyme Multiplied Immunoassay Technique Feces - virology Female Fever - complications Gastroenteritis - complications Gastroenteritis - epidemiology Gastroenteritis - virology Hospitalization Humans Infant Infant, Newborn Male Pakistan - epidemiology Population Surveillance Prevalence Rotavirus - isolation & purification Rotavirus - pathogenicity Rotavirus infections Rotavirus Infections - epidemiology Rotavirus Infections - virology Time Factors |
title | Rota virus Diarrhea in Hospitalized Children |
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