Rota virus Diarrhea in Hospitalized Children

To determine the frequency and clinical features of Rota virus diarrhea in children presenting in a tertiary care hospital. A cross-sectional, observational study. National Institute of Child Health, Karachi, from January to June 2007. A total of three hundred children of either gender aged 1 month...

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Veröffentlicht in:Journal of the College of Physicians and Surgeons--Pakistan 2014-02, Vol.24 (2), p.114-117
Hauptverfasser: Habib, Muhammad Irfan, Kazi, Sayyeda Ghazala, Ahmed Khan, Khalid Mehmood, Zia, Nukhba
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container_issue 2
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container_title Journal of the College of Physicians and Surgeons--Pakistan
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creator Habib, Muhammad Irfan
Kazi, Sayyeda Ghazala
Ahmed Khan, Khalid Mehmood
Zia, Nukhba
description To determine the frequency and clinical features of Rota virus diarrhea in children presenting in a tertiary care hospital. A cross-sectional, observational study. National Institute of Child Health, Karachi, from January to June 2007. A total of three hundred children of either gender aged 1 month to 5 years, who presented with diarrhea of < 7 days as a primary illness were enrolled. Children with bloody diarrhea or nosocomial gastroenteritis acquired during hospitalization for other disease were not included. Detection of Rota virus in stool was done by enzyme linked immunoassay. Out of 300 children, 188 (63%) tested positive and 112 (37%) tested negative for Rota virus. Positive Rota virus cases in 7 - 12 months of age was (n = 34, 18.08%). Overall, 151 (80.3%) children with Rota virus were less than 3 years old. 182 (60.7%) had fever, 118 (39.3%) had vomiting and 156 (82.9%) children had both fever and vomiting. This study shows that Rota virus is a common organism causing diarrhea in children less than 3 years of age. There is a need to incorporate Rota virus vaccine in the national EPI program to decrease the disease burden as highlighted in this study.
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A cross-sectional, observational study. National Institute of Child Health, Karachi, from January to June 2007. A total of three hundred children of either gender aged 1 month to 5 years, who presented with diarrhea of &lt; 7 days as a primary illness were enrolled. Children with bloody diarrhea or nosocomial gastroenteritis acquired during hospitalization for other disease were not included. Detection of Rota virus in stool was done by enzyme linked immunoassay. Out of 300 children, 188 (63%) tested positive and 112 (37%) tested negative for Rota virus. Positive Rota virus cases in 7 - 12 months of age was (n = 34, 18.08%). Overall, 151 (80.3%) children with Rota virus were less than 3 years old. 182 (60.7%) had fever, 118 (39.3%) had vomiting and 156 (82.9%) children had both fever and vomiting. This study shows that Rota virus is a common organism causing diarrhea in children less than 3 years of age. 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subjects Causes of
Child, Preschool
Cross-Sectional Studies
Demographic aspects
Diarrhea - epidemiology
Diarrhea - etiology
Diarrhea - virology
Diarrhea in children
Distribution
Enzyme Multiplied Immunoassay Technique
Feces - virology
Female
Fever - complications
Gastroenteritis - complications
Gastroenteritis - epidemiology
Gastroenteritis - virology
Hospitalization
Humans
Infant
Infant, Newborn
Male
Pakistan - epidemiology
Population Surveillance
Prevalence
Rotavirus - isolation & purification
Rotavirus - pathogenicity
Rotavirus infections
Rotavirus Infections - epidemiology
Rotavirus Infections - virology
Time Factors
title Rota virus Diarrhea in Hospitalized Children
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