Biochemical and morphological studies of ammonium perfluorooctanoate-induced hepatomegaly and peroxisome proliferation

Ammonium perfluorooctanoate (APFO) is known to induce a striking hepatomegaly in rats. The purpose of these studies was to determine the causes of the hepatomegaly and compare the effect to other liver-enlarging compounds. Since the total hepatic DNA content was similar in control and APFO-treated r...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental and molecular pathology 1987-08, Vol.47 (1), p.98-109
Hauptverfasser:	Pastoor, Timothy P., Lee, Ki Poong, Perri, Marie A., Gillies, Peter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Body Weight Caprylates - pharmacology Chemical and industrial products toxicology. Toxic occupational diseases DNA - analysis Endoplasmic Reticulum - enzymology Endoplasmic Reticulum - ultrastructure Fluorocarbons - pharmacology Hepatomegaly - chemically induced Hepatomegaly - enzymology Hepatomegaly - metabolism Hepatomegaly - pathology Lipids - biosynthesis Lipids - blood Liver - enzymology Liver - metabolism Liver - ultrastructure Male Medical sciences Microbodies - enzymology Microbodies - ultrastructure Microscopy, Electron Microsomes - enzymology Mitochondria, Liver - enzymology Mitochondria, Liver - ultrastructure Organ Size Rats Toxicology Various organic compounds
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!