c-Jun NH sub(2)-terminal kinase is a critical node in the death of CD4 super(+)CD8 super(+) thymocytes during Salmonella enterica serovar Typhimurium infection
Thymic atrophy, due to the depletion of CD4 super(+)CD8 super(+) thymocytes, is observed during infections with numerous pathogens. Several mechanisms, such as glucocorticoids and inflammatory cytokines, are known to be involved in this process; however, the roles of intracellular signaling molecule...
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Veröffentlicht in: | European journal of immunology 2014-01, Vol.44 (1), p.137-149 |
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