c-Jun NH sub(2)-terminal kinase is a critical node in the death of CD4 super(+)CD8 super(+) thymocytes during Salmonella enterica serovar Typhimurium infection

Thymic atrophy, due to the depletion of CD4 super(+)CD8 super(+) thymocytes, is observed during infections with numerous pathogens. Several mechanisms, such as glucocorticoids and inflammatory cytokines, are known to be involved in this process; however, the roles of intracellular signaling molecule...

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Veröffentlicht in:European journal of immunology 2014-01, Vol.44 (1), p.137-149
Hauptverfasser: Deobagkar-Lele, Mukta, Victor, Emmanuel S, Nandi, Dipankar
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Sprache:eng
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