Structural insights into the histone H1-nucleosome complex

Linker H1 histones facilitate formation of higher-order chromatin structures and play important roles in various cell functions. Despite several decades of effort, the structural basis of how H1 interacts with the nucleosome remains elusive. Here, we investigated Drosophila H1 in complex with the nu...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2013-11, Vol.110 (48), p.19390-19395
Hauptverfasser:	Zhou, Bing-Rui, Feng, Hanqiao, Kato, Hidenori, Dia, Liang, Yang, Yuedong, Zhou, Yaoqi, Bai, Yawen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biochemistry Biological Sciences Biophysics Calorimetry Chromatin Deoxyribonucleic acid DNA Drosophila Genetic mutation Histones Histones - chemistry Histones - genetics Insects Macromolecular Substances - chemistry Magnetic Resonance Spectroscopy Models, Molecular Molecular Conformation Molecular Sequence Data Mutagenesis, Site-Directed NMR Nuclear magnetic resonance nuclear magnetic resonance spectroscopy Nucleic acids Nucleosomes Nucleosomes - chemistry Protein Binding Proteins Spectrum analysis Spin labels
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