9G4+ Antibodies Isolated from HIV-Infected Patients Neutralize HIV-1 and Have Distinct Autoreactivity Profiles: e85098

Potent HIV-1 specific broadly neutralizing antibodies (BNA) are uncommon in HIV infected individuals, and have proven hard to elicit by vaccination. Several, isolated monoclonal BNA are polyreactive and also recognize self-antigens, suggesting a breach of immune tolerance in persons living with HIV...

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Veröffentlicht in:	PloS one 2013-12, Vol.8 (12)
Hauptverfasser:	Alcena, Danielle C, Kobie, James J, Kaminski, Denise A, Rosenberg, Alexander F, Mattiacio, Jonelle L, Brewer, Matthew, Dewhurst, Stephen, Dykes, Carrie, Jin, Xia, Keefer, Michael C
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Human immunodeficiency virus 1
Online-Zugang:	Volltext
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