Targeting of DICE1 tumor suppressor by Epstein–Barr virus‐encoded miR‐BART3 microRNA in nasopharyngeal carcinoma

Latent infection with Epstein–Barr virus (EBV) is associated with several types of malignancies including nasopharyngeal carcinoma (NPC), which is particularly more prevalent in Southern China. EBV expresses at least 44 mature microRNAs (miRNAs) to modulate the activity of viral and cellular RNAs, b...

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Veröffentlicht in:	International journal of cancer 2013-07, Vol.133 (1), p.79-87
Hauptverfasser:	Lei, Ting, Yuen, Kit‐San, Xu, Rui, Tsao, Sai Wah, Chen, Honglin, Li, Mengfeng, Kok, Kin‐Hang, Jin, Dong‐Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Cancer Carcinoma China DICE1 tumor suppressor Down-Regulation EBV‐encoded microRNAs Epstein-Barr virus Epstein-Barr Virus Infections - complications Epstein-Barr Virus Infections - metabolism Epstein–Barr virus (EBV) Gene Expression Regulation, Neoplastic Gene Silencing Genes HEK293 Cells HeLa Cells Herpesvirus 4, Human Humans Infectious diseases Laryngeal cancer Medical research Medical sciences MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - virology Reverse Transcriptase Polymerase Chain Reaction Ribosomal Proteins - genetics Ribosomal Proteins - metabolism Tumor Suppressor Proteins - genetics Tumor Suppressor Proteins - metabolism Tumors Viral diseases
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