Evaluation of the Radical Scavenging Activity of Resorcinarenes by DPPH• Free Radical Assay

Evaluation of the Radical Scavenging Activity of Resorcinarenes by DPPH• Free Radical Assay

A series of methyl-pendanted resorcinarene derivatives have been synthesised and evaluated for radical scavenging potential by using a colorimetric DPPH[bullet] assay to reveal their utility as potent radical scavengers. An evaluation of the efficiencies in relation to the number of DPPH[bullet] mol...

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Veröffentlicht in:Journal of chemical research 2010-08, Vol.34 (8), p.440-444
Hauptverfasser: Bishnoi, Anjali, Chawla, Har Mohindra, Pant, Nalin, Mrig, Sarika, Kumar, Satish
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container_issue 8
container_start_page 440
container_title Journal of chemical research
container_volume 34
creator Bishnoi, Anjali
Chawla, Har Mohindra
Pant, Nalin
Mrig, Sarika
Kumar, Satish
description A series of methyl-pendanted resorcinarene derivatives have been synthesised and evaluated for radical scavenging potential by using a colorimetric DPPH[bullet] assay to reveal their utility as potent radical scavengers. An evaluation of the efficiencies in relation to the number of DPPH[bullet] molecules reduced by one molecule of antioxidant establishes that resorcinarene can reduce approximately eight DPPH[bullet] molecules at a fairly lower stoichiometric concentration. This behaviour is compared to that of well known radical scavengers (?-tocopherol, BHT and resorcinol) frequently used as reference compounds in scientific evaluations.
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title Evaluation of the Radical Scavenging Activity of Resorcinarenes by DPPH• Free Radical Assay
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