Leucocytosis in a case of sarcoidosis with pleural involvement--an unknown association
A case of biopsy-proven sarcoidosis with pleural and lung parenchymal involvement is reported. The resolution of neutrophilia and other disease manifestations with azathioprine points towards sarcoidosis being the probable cause. GG, 45 years old male, presented with fever and right-sided chest pain...
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| Veröffentlicht in: | Journal of the Association of Physicians of India 2013-05, Vol.61 (5), p.343-345 |
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| container_title | Journal of the Association of Physicians of India |
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| creator | Bhattacharyya, Parthasarathi Nag, Saikat Bardhan, Sujan Acharyya, Dipabali Roychowdhury, Arindam Gupta, Anirban |
| description | A case of biopsy-proven sarcoidosis with pleural and lung parenchymal involvement is reported. The resolution of neutrophilia and other disease manifestations with azathioprine points towards sarcoidosis being the probable cause. GG, 45 years old male, presented with fever and right-sided chest pain with biochemical features of granulomatous hepatitis and apparently unexplained leucocytosis. Azathioprine 100 mg daily was started; he improved dramatically within 3 weeks with disappearance of pain and normalization of alkaline phosphatase and leucocytosis. All clinical, biochemical and hematological parameters improved subsequently. There were no significant side effects and the patient is doing well after more than three years on azathioprine. The resolution of neutrophilia on treatment of sarcoidosis suggests a causal relationship. However, further follow-up is essential to screen for future hematological abnormalities. |
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The resolution of neutrophilia and other disease manifestations with azathioprine points towards sarcoidosis being the probable cause. GG, 45 years old male, presented with fever and right-sided chest pain with biochemical features of granulomatous hepatitis and apparently unexplained leucocytosis. Azathioprine 100 mg daily was started; he improved dramatically within 3 weeks with disappearance of pain and normalization of alkaline phosphatase and leucocytosis. All clinical, biochemical and hematological parameters improved subsequently. There were no significant side effects and the patient is doing well after more than three years on azathioprine. The resolution of neutrophilia on treatment of sarcoidosis suggests a causal relationship. However, further follow-up is essential to screen for future hematological abnormalities.</description><identifier>ISSN: 0004-5772</identifier><identifier>PMID: 24482951</identifier><language>eng</language><publisher>India</publisher><subject>Humans ; Leukocytosis - diagnosis ; Leukocytosis - etiology ; Leukocytosis - therapy ; Male ; Middle Aged ; Pleural Diseases - complications ; Pleural Diseases - diagnosis ; Pleural Diseases - therapy ; Sarcoidosis - complications ; Sarcoidosis - diagnosis ; Sarcoidosis - therapy</subject><ispartof>Journal of the Association of Physicians of India, 2013-05, Vol.61 (5), p.343-345</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24482951$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bhattacharyya, Parthasarathi</creatorcontrib><creatorcontrib>Nag, Saikat</creatorcontrib><creatorcontrib>Bardhan, Sujan</creatorcontrib><creatorcontrib>Acharyya, Dipabali</creatorcontrib><creatorcontrib>Roychowdhury, Arindam</creatorcontrib><creatorcontrib>Gupta, Anirban</creatorcontrib><title>Leucocytosis in a case of sarcoidosis with pleural involvement--an unknown association</title><title>Journal of the Association of Physicians of India</title><addtitle>J Assoc Physicians India</addtitle><description>A case of biopsy-proven sarcoidosis with pleural and lung parenchymal involvement is reported. The resolution of neutrophilia and other disease manifestations with azathioprine points towards sarcoidosis being the probable cause. GG, 45 years old male, presented with fever and right-sided chest pain with biochemical features of granulomatous hepatitis and apparently unexplained leucocytosis. Azathioprine 100 mg daily was started; he improved dramatically within 3 weeks with disappearance of pain and normalization of alkaline phosphatase and leucocytosis. All clinical, biochemical and hematological parameters improved subsequently. There were no significant side effects and the patient is doing well after more than three years on azathioprine. The resolution of neutrophilia on treatment of sarcoidosis suggests a causal relationship. 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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Humans Leukocytosis - diagnosis Leukocytosis - etiology Leukocytosis - therapy Male Middle Aged Pleural Diseases - complications Pleural Diseases - diagnosis Pleural Diseases - therapy Sarcoidosis - complications Sarcoidosis - diagnosis Sarcoidosis - therapy |
| title | Leucocytosis in a case of sarcoidosis with pleural involvement--an unknown association |
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