Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer

Increasing evidence shows that abnormal microRNAs (miRNAs) expression is involved in tumorigenesis. They might be the novel biomarkers or therapeutic targets in disease treatment. miR-29 family was previously reported to act as tumor suppressors or oncogenes in diverse cancers. However, their accura...

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Veröffentlicht in:	Carcinogenesis (New York) 2014-02, Vol.35 (2), p.497-506
Hauptverfasser:	Gong, Jianan, Li, Jianxiong, Wang, Yi, Liu, Changzheng, Jia, Hongyan, Jiang, Chongliang, Wang, Yuxuan, Luo, Min, Zhao, Hongmei, Dong, Lei, Song, Wei, Wang, Fang, Wang, Weibin, Zhang, Junwu, Yu, Jia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Blotting, Northern Blotting, Western Cell Cycle Cell Movement Cell Proliferation Cyclin D2 - genetics Cyclin D2 - metabolism Female Fluorescent Antibody Technique Gastric Mucosa - metabolism Humans Immunoenzyme Techniques Matrix Metalloproteinase 2 - genetics Matrix Metalloproteinase 2 - metabolism Mice Mice, Nude MicroRNAs - genetics Neoplasm Invasiveness Real-Time Polymerase Chain Reaction Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Stomach - pathology Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Tumor Cells, Cultured
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