Synthesis, characterization, cytotoxicity and antibacterial activity of an anthracenyl-linked bis(pyrazolyl)methane ligand and its zinc(II) complexes

Three novel Zn(II) complexes (1–3) with 1,1′-(anthracen-9-ylmethylene)bis(1H-pyrazole) (L2) have been prepared and structurally characterized by X-ray crystallography. Among them, 1 is a binuclear Zn(II) complex while 2 and 3 are mononuclear. The in vitro cytotoxic and antibacterial activities of th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of medicinal chemistry 2014-01, Vol.72, p.46-51
Hauptverfasser:	Ruan, Ban-Feng, Zhu, Ying-Zhong, Liu, Wan-Ding, Song, Bao-An, Tian, Yu-Peng
Format:	Artikel
Sprache:	eng
Schlagworte:	1,1′-(Anthracen-9-ylmethylene)bis(1H-pyrazole) Anthracenes - chemistry Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibacterial activity Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Cell Line, Tumor Cell Proliferation - drug effects Crystal structure Crystallography, X-Ray Cytotoxicity Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Humans Methane - analogs & derivatives Methane - chemistry Microbial Sensitivity Tests Models, Molecular Molecular Structure Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Organometallic Compounds - pharmacology Pyrazoles - chemistry Structure-Activity Relationship Zinc - chemistry Zinc(II) complex
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!