Fear response failed to return in AAB extinction paradigm accompanied with increased NR2B and GluR1 per845 in hippocampal CA1
Highlights • Extinction training in the conditioning context (AAB) failed to show renewal. • Hippocampal CA1 may be involved in the modulation of fear expression and extinction. • The modulation seems to be embodied in regulation of protein expression in BLA.
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| Veröffentlicht in: | Neuroscience 2014-02, Vol.260, p.1-11 |
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| container_title | Neuroscience |
| container_volume | 260 |
| creator | Xue, L Li, Z.D Chen, Z.X Wang, X.G Shi, Y.W Zhao, H |
| description | Highlights • Extinction training in the conditioning context (AAB) failed to show renewal. • Hippocampal CA1 may be involved in the modulation of fear expression and extinction. • The modulation seems to be embodied in regulation of protein expression in BLA. |
| doi_str_mv | 10.1016/j.neuroscience.2013.12.014 |
| format | Article |
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| ispartof | Neuroscience, 2014-02, Vol.260, p.1-11 |
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| language | eng |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Amygdala - metabolism Animals Biological and medical sciences CA1 Region, Hippocampal - drug effects CA1 Region, Hippocampal - metabolism CA1 Region, Hippocampal - physiology extinction Extinction, Psychological - drug effects Fear - drug effects Fear - psychology fear memory Fundamental and applied biological sciences. Psychology Male muscimol Neural Pathways Neurology phosphorylation Rats Rats, Sprague-Dawley Receptors, AMPA - metabolism Receptors, N-Methyl-D-Aspartate - metabolism renewal Vertebrates: nervous system and sense organs |
| title | Fear response failed to return in AAB extinction paradigm accompanied with increased NR2B and GluR1 per845 in hippocampal CA1 |
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