Identification of a putative antigen receptor on fish nonspecific cytotoxic cells with monoclonal antibodies

In the present study mAb were derived against flow cytometry (FCM) purified fish (Ictalurus punctatus) nonspecific cytotoxic cells (NCC). mAb 5C6.10.4 and 6D3.2.10 produced 60 to 65% inhibition of lysis of NC-37 target cells (a human B-lymphoblastoid cell line) by unfractionated NCC. mAb 2B2.4.9 and...

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Veröffentlicht in:	The Journal of immunology (1950) 1988-07, Vol.141 (1), p.324-332
Hauptverfasser:	Evans, DL, Jaso-Friedmann, L, Smith, EE, Jr, St. John, A, Koren, HS, Harris, DT
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antibodies Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - physiology antigens Binding Sites, Antibody Biological and medical sciences Catfishes - immunology Cytotoxicity Tests, Immunologic - methods Cytotoxicity, Immunologic Epitopes - immunology Female Freshwater Fundamental and applied biological sciences. Psychology Fundamental immunology General aspects. Ontogeny. Phylogeny Hybridomas - metabolism Ictaluridae - immunology Ictalurus punctatus identification Immunity, Cellular Immunobiology immunology Immunosuppressive Agents - physiology Kidney - cytology lymphoid cells Male Mice Mice, Inbred BALB C monoclonal antibodies receptors Receptors, Antigen - immunology Receptors, Antigen - isolation & purification Spleen - cytology
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