A randomized multicenter phase II trial on the efficacy of a hydrocolloid dressing containing ceramide with a low-friction external surface for hand-foot skin reaction caused by sorafenib in patients with renal cell carcinoma

The purpose of this study was to investigate the usefulness of a hydrocolloid dressing containing ceramide for hand-foot skin reaction (HFSR) on the soles of the feet in metastatic renal cell carcinoma (RCC) patients treated with sorafenib. Patients with grade 1 HFSR on the soles of the feet were ra...

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Veröffentlicht in:	Annals of oncology 2014-02, Vol.25 (2), p.472-476
Hauptverfasser:	Shinohara, N., Nonomura, N., Eto, M., Kimura, G., Minami, H., Tokunaga, S., Naito, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Bandages, Hydrocolloid Biological and medical sciences Carcinoma, Renal Cell - drug therapy Carcinoma, Renal Cell - secondary ceramide Ceramides - administration & dosage Female hand-foot skin reaction Hand-Foot Syndrome - therapy Humans hydrocolloid dressing Kaplan-Meier Estimate Kidney Neoplasms - drug therapy Kidney Neoplasms - pathology Kidneys Male Medical sciences Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Nephrology. Urinary tract diseases Niacinamide - adverse effects Niacinamide - analogs & derivatives Niacinamide - therapeutic use Pharmacology. Drug treatments Phenylurea Compounds - adverse effects Phenylurea Compounds - therapeutic use renal cell carcinoma Sorafenib Surface Properties Treatment Outcome Tumors Tumors of the urinary system
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