Corticosteroids and Allergies to Contrast Material
To the Editor: The data presented and the conclusions drawn by Lasser et al. (Oct. 1 issue)* about the effect of steroids on the incidence of severe (their Grade III) reactions in patients given ionic contrast mediums seem likely to mislead all but the most careful reader. Patients receiving the ion...
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Veröffentlicht in: | The New England journal of medicine 1988-03, Vol.318 (13), p.856-857 |
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container_title | The New England journal of medicine |
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creator | Ackroyd, J F |
description | To the Editor:
The data presented and the conclusions drawn by Lasser et al. (Oct. 1 issue)* about the effect of steroids on the incidence of severe (their Grade III) reactions in patients given ionic contrast mediums seem likely to mislead all but the most careful reader. Patients receiving the ionic contrast mediums were given either one or two doses of oral methylprednisolone before the medium was injected. Two control groups received one or two placebo tablets.
The single dose of methylprednisolone did not reduce the incidence of adverse reactions. As compared with placebo, two doses of steroid did not . . .
No extract is available for articles shorter than 400 words. |
doi_str_mv | 10.1056/NEJM198803313181314 |
format | Article |
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The data presented and the conclusions drawn by Lasser et al. (Oct. 1 issue)* about the effect of steroids on the incidence of severe (their Grade III) reactions in patients given ionic contrast mediums seem likely to mislead all but the most careful reader. Patients receiving the ionic contrast mediums were given either one or two doses of oral methylprednisolone before the medium was injected. Two control groups received one or two placebo tablets.
The single dose of methylprednisolone did not reduce the incidence of adverse reactions. As compared with placebo, two doses of steroid did not . . .
No extract is available for articles shorter than 400 words.</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM198803313181314</identifier><identifier>PMID: 3352668</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Contrast Media - adverse effects ; Drug Hypersensitivity - prevention & control ; Humans ; Methylprednisolone - therapeutic use</subject><ispartof>The New England journal of medicine, 1988-03, Vol.318 (13), p.856-857</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c367t-6f6ba59cbe3a8aa2bf6d5f66061229b19c564ec6d11e79d695bd69d8c80870452</citedby><cites>FETCH-LOGICAL-c367t-6f6ba59cbe3a8aa2bf6d5f66061229b19c564ec6d11e79d695bd69d8c80870452</cites></display><links><openurl>$$Topenurl_article</openurl><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>776</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3352668$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ackroyd, J F</creatorcontrib><title>Corticosteroids and Allergies to Contrast Material</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
The data presented and the conclusions drawn by Lasser et al. (Oct. 1 issue)* about the effect of steroids on the incidence of severe (their Grade III) reactions in patients given ionic contrast mediums seem likely to mislead all but the most careful reader. Patients receiving the ionic contrast mediums were given either one or two doses of oral methylprednisolone before the medium was injected. Two control groups received one or two placebo tablets.
The single dose of methylprednisolone did not reduce the incidence of adverse reactions. As compared with placebo, two doses of steroid did not . . .
No extract is available for articles shorter than 400 words.</description><subject>Contrast Media - adverse effects</subject><subject>Drug Hypersensitivity - prevention & control</subject><subject>Humans</subject><subject>Methylprednisolone - therapeutic use</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>false</fulltext><rsrctype>article</rsrctype><creationdate>1988</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UMtKxDAUDaKM4-gXiNCVG6nm3WQ5lPHFjG50HdIklQ5tMyaZhX9vpIMr8cK9d3EecA4AlwjeIsj43cvqeYOkEJAQRJDIS4_AHDFCSkohPwZzCLEoaSXJKTiLcQvzICpnYEYIw5yLOcC1D6kzPiYXfGdjoUdbLPvehY_OxSL5ovZjCjqmYqMzp9P9OThpdR_dxeEvwPv96q1-LNevD0_1cl0awqtU8pY3mknTOKKF1rhpuWUt55AjjGWDpGGcOsMtQq6SlkvW5GOFEVBUkDK8ANeT7y74z72LSQ1dNK7v9ej8PqqcBEspYCaSiWiCjzG4Vu1CN-jwpRBUP02pP5rKqquD_b4ZnP3VHKrJ-M2ED0NUo9sO_7p9A_1lbuc</recordid><startdate>19880331</startdate><enddate>19880331</enddate><creator>Ackroyd, J F</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>19880331</creationdate><title>Corticosteroids and Allergies to Contrast Material</title><author>Ackroyd, J F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-6f6ba59cbe3a8aa2bf6d5f66061229b19c564ec6d11e79d695bd69d8c80870452</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1988</creationdate><topic>Contrast Media - adverse effects</topic><topic>Drug Hypersensitivity - prevention & control</topic><topic>Humans</topic><topic>Methylprednisolone - therapeutic use</topic><toplevel>peer_reviewed</toplevel><creatorcontrib>Ackroyd, J F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>no_fulltext</fulltext></delivery><addata><au>Ackroyd, J F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Corticosteroids and Allergies to Contrast Material</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1988-03-31</date><risdate>1988</risdate><volume>318</volume><issue>13</issue><spage>856</spage><epage>857</epage><pages>856-857</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
The data presented and the conclusions drawn by Lasser et al. (Oct. 1 issue)* about the effect of steroids on the incidence of severe (their Grade III) reactions in patients given ionic contrast mediums seem likely to mislead all but the most careful reader. Patients receiving the ionic contrast mediums were given either one or two doses of oral methylprednisolone before the medium was injected. Two control groups received one or two placebo tablets.
The single dose of methylprednisolone did not reduce the incidence of adverse reactions. As compared with placebo, two doses of steroid did not . . .
No extract is available for articles shorter than 400 words.</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>3352668</pmid><doi>10.1056/NEJM198803313181314</doi><tpages>2</tpages></addata></record> |
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ispartof | The New England journal of medicine, 1988-03, Vol.318 (13), p.856-857 |
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language | eng |
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source | MEDLINE |
subjects | Contrast Media - adverse effects Drug Hypersensitivity - prevention & control Humans Methylprednisolone - therapeutic use |
title | Corticosteroids and Allergies to Contrast Material |
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