Inflammatory and fibrotic proteins proteomically identified as key protein constituents in urine and stone matrix of patients with kidney calculi

To uncover whether urinary proteins are incorporated into stones, the proteomic profiles of kidney stones and urine collected from the same patients have to be explored. We employed 1D-PAGE and nanoHPLC-ESI-MS/MS to analyze the proteomes of kidney stone matrix (n=16), nephrolithiatic urine (n=14) an...

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Veröffentlicht in:	Clinica chimica acta 2014-02, Vol.429, p.81-89
Hauptverfasser:	Boonla, Chanchai, Tosukhowong, Piyaratana, Spittau, Björn, Schlosser, Andreas, Pimratana, Chaowat, Krieglstein, Kerstin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers - metabolism Biomarkers - urine Female Fibronectin Fibrosis Gene Expression Regulation Humans Inflammation Inflammation - metabolism Kidney - metabolism Kidney - pathology Kidney Calculi - metabolism Kidney Calculi - pathology Kidney Calculi - urine Kidney stone Male Middle Aged Proteomics S100A8
Online-Zugang:	Volltext
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