cis-Urocanic acid as a potential nickel(ii) binding molecule in the human skin

cis -Urocanic acid, a derivative of histidine, is one of the essential components of human skin. We found that it can bind nickel( ii ) ions in a pH-dependent manner, with the dissociation constant in the low millimolar range, as revealed by potentiometry, and confirmed by isothermal titration calor...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2014-01, Vol.43 (8), p.3196-321
Hauptverfasser:	Wezynfeld, Nina Ewa, Goch, Wojciech, Bal, Wojciech, Fr czyk, Tomasz
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Constants Derivatives Electrical measurements Histidine Histidine - chemistry Human Humans Hydrogen-Ion Concentration Ions - chemistry Isomerism Nickel - chemistry Nickel - metabolism Organisms Skin - chemistry Skin - metabolism Thermodynamics Titration calorimetry Ultraviolet Rays Urocanic Acid - chemistry Urocanic Acid - metabolism
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