In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline

Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commerc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Antimicrobial Agents and Chemotherapy 2014-02, Vol.58 (2), p.1127-1135
Hauptverfasser: MACONE, A. B, CARUSO, B. K, LEAHY, R. G, DONATELLI, J, WEIR, S, DRAPER, M. P, TANAKA, S. K, LEVY, S. B
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1135
container_issue 2
container_start_page 1127
container_title Antimicrobial Agents and Chemotherapy
container_volume 58
creator MACONE, A. B
CARUSO, B. K
LEAHY, R. G
DONATELLI, J
WEIR, S
DRAPER, M. P
TANAKA, S. K
LEVY, S. B
description Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
doi_str_mv 10.1128/AAC.01242-13
format Article
fullrecord <record><control><sourceid>proquest_pasca</sourceid><recordid>TN_cdi_proquest_miscellaneous_1492720115</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1492720115</sourcerecordid><originalsourceid>FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</originalsourceid><addsrcrecordid>eNp10U2LFDEQBuBGFHdcvXmW9iAobK_56KSTi9AMfiws7kUFT6GSqd7J0p2sSc_I_HszO-OqB0-hqIcqKm9VPafknFKm3vb98pxQ1rKG8gfVghKtGim0fFgtCJGyaRVpT6onOd-QUgtNHlcnRWuhlVhU3y9C_c3PKdYQVvVdsY11H2Zvwc2YPIx172a_9bPHXMehvppgBW7nRh_wrIb6c9xiMZMPccJ5vRuPvafVowHGjM-O72n19cP7L8tPzeXVx4tlf9mAoN3cCKmV5QOltnUELekYdpJxbjsOvLVAmEBiQckOrOCqW2mJqJzV2CItt_HT6t1h7u3GTrhyGOYEo7lNfoK0MxG8-bcT_Npcx63hmhKlWBnw-jggxR8bzLOZfHY4jhAwbrKhrWYdI5SKQs8O1KWYc8Lhfg0lZp-GKWmYuzQM5YW_OXDIEzM3cZNC-Yn_2Rd_n3E_-HdUBbw6AsgOxiFBcD7_cYoJKuXevTy4tb9e__QJTdluAJwRyrD95o7_Aqimqb4</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1492720115</pqid></control><display><type>article</type><title>In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><creator>MACONE, A. B ; CARUSO, B. K ; LEAHY, R. G ; DONATELLI, J ; WEIR, S ; DRAPER, M. P ; TANAKA, S. K ; LEVY, S. B</creator><creatorcontrib>MACONE, A. B ; CARUSO, B. K ; LEAHY, R. G ; DONATELLI, J ; WEIR, S ; DRAPER, M. P ; TANAKA, S. K ; LEVY, S. B</creatorcontrib><description>Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions &amp; Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       </description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.01242-13</identifier><identifier>PMID: 24295985</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject><![CDATA[Animals ; Anti-Bacterial Agents ; Anti-Bacterial Agents - chemical synthesis ; Anti-Bacterial Agents - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; ATP-Binding Cassette Transporters - antagonists & inhibitors ; ATP-Binding Cassette Transporters - genetics ; ATP-Binding Cassette Transporters - metabolism ; Bacterial Infections ; Bacterial Infections - drug therapy ; Bacterial Infections - microbiology ; Biological and medical sciences ; Drug Resistance, Multiple, Bacterial - drug effects ; Enterococcus ; Enterococcus - drug effects ; Enterococcus - growth & development ; Escherichia coli ; Escherichia coli - drug effects ; Escherichia coli - growth & development ; Experimental Therapeutics ; Gene Expression ; Haemophilus influenzae ; Haemophilus influenzae - drug effects ; Haemophilus influenzae - growth & development ; Male ; Medical sciences ; Methicillin-Resistant Staphylococcus aureus ; Methicillin-Resistant Staphylococcus aureus - drug effects ; Methicillin-Resistant Staphylococcus aureus - growth & development ; Mice ; Microbial Sensitivity Tests ; Peritoneum - drug effects ; Peritoneum - microbiology ; Pharmacology. Drug treatments ; Ribosomes - drug effects ; Staphylococcus aureus ; Staphylococcus aureus - drug effects ; Staphylococcus aureus - growth & development ; Streptococcus pneumoniae ; Streptococcus pneumoniae - drug effects ; Streptococcus pneumoniae - growth & development ; Tetracyclines ; Tetracyclines - chemical synthesis ; Tetracyclines - pharmacology]]></subject><ispartof>Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.1127-1135</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2014, American Society for Microbiology. All Rights Reserved. 2014 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</citedby><cites>FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910882/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910882/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=28251665$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24295985$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MACONE, A. B</creatorcontrib><creatorcontrib>CARUSO, B. K</creatorcontrib><creatorcontrib>LEAHY, R. G</creatorcontrib><creatorcontrib>DONATELLI, J</creatorcontrib><creatorcontrib>WEIR, S</creatorcontrib><creatorcontrib>DRAPER, M. P</creatorcontrib><creatorcontrib>TANAKA, S. K</creatorcontrib><creatorcontrib>LEVY, S. B</creatorcontrib><title>In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions &amp; Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       </description><subject>Animals</subject><subject>Anti-Bacterial Agents</subject><subject>Anti-Bacterial Agents - chemical synthesis</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>ATP-Binding Cassette Transporters - antagonists &amp; inhibitors</subject><subject>ATP-Binding Cassette Transporters - genetics</subject><subject>ATP-Binding Cassette Transporters - metabolism</subject><subject>Bacterial Infections</subject><subject>Bacterial Infections - drug therapy</subject><subject>Bacterial Infections - microbiology</subject><subject>Biological and medical sciences</subject><subject>Drug Resistance, Multiple, Bacterial - drug effects</subject><subject>Enterococcus</subject><subject>Enterococcus - drug effects</subject><subject>Enterococcus - growth &amp; development</subject><subject>Escherichia coli</subject><subject>Escherichia coli - drug effects</subject><subject>Escherichia coli - growth &amp; development</subject><subject>Experimental Therapeutics</subject><subject>Gene Expression</subject><subject>Haemophilus influenzae</subject><subject>Haemophilus influenzae - drug effects</subject><subject>Haemophilus influenzae - growth &amp; development</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methicillin-Resistant Staphylococcus aureus</subject><subject>Methicillin-Resistant Staphylococcus aureus - drug effects</subject><subject>Methicillin-Resistant Staphylococcus aureus - growth &amp; development</subject><subject>Mice</subject><subject>Microbial Sensitivity Tests</subject><subject>Peritoneum - drug effects</subject><subject>Peritoneum - microbiology</subject><subject>Pharmacology. Drug treatments</subject><subject>Ribosomes - drug effects</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus aureus - drug effects</subject><subject>Staphylococcus aureus - growth &amp; development</subject><subject>Streptococcus pneumoniae</subject><subject>Streptococcus pneumoniae - drug effects</subject><subject>Streptococcus pneumoniae - growth &amp; development</subject><subject>Tetracyclines</subject><subject>Tetracyclines - chemical synthesis</subject><subject>Tetracyclines - pharmacology</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10U2LFDEQBuBGFHdcvXmW9iAobK_56KSTi9AMfiws7kUFT6GSqd7J0p2sSc_I_HszO-OqB0-hqIcqKm9VPafknFKm3vb98pxQ1rKG8gfVghKtGim0fFgtCJGyaRVpT6onOd-QUgtNHlcnRWuhlVhU3y9C_c3PKdYQVvVdsY11H2Zvwc2YPIx172a_9bPHXMehvppgBW7nRh_wrIb6c9xiMZMPccJ5vRuPvafVowHGjM-O72n19cP7L8tPzeXVx4tlf9mAoN3cCKmV5QOltnUELekYdpJxbjsOvLVAmEBiQckOrOCqW2mJqJzV2CItt_HT6t1h7u3GTrhyGOYEo7lNfoK0MxG8-bcT_Npcx63hmhKlWBnw-jggxR8bzLOZfHY4jhAwbrKhrWYdI5SKQs8O1KWYc8Lhfg0lZp-GKWmYuzQM5YW_OXDIEzM3cZNC-Yn_2Rd_n3E_-HdUBbw6AsgOxiFBcD7_cYoJKuXevTy4tb9e__QJTdluAJwRyrD95o7_Aqimqb4</recordid><startdate>20140201</startdate><enddate>20140201</enddate><creator>MACONE, A. B</creator><creator>CARUSO, B. K</creator><creator>LEAHY, R. G</creator><creator>DONATELLI, J</creator><creator>WEIR, S</creator><creator>DRAPER, M. P</creator><creator>TANAKA, S. K</creator><creator>LEVY, S. B</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20140201</creationdate><title>In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline</title><author>MACONE, A. B ; CARUSO, B. K ; LEAHY, R. G ; DONATELLI, J ; WEIR, S ; DRAPER, M. P ; TANAKA, S. K ; LEVY, S. B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>Anti-Bacterial Agents</topic><topic>Anti-Bacterial Agents - chemical synthesis</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>ATP-Binding Cassette Transporters - antagonists &amp; inhibitors</topic><topic>ATP-Binding Cassette Transporters - genetics</topic><topic>ATP-Binding Cassette Transporters - metabolism</topic><topic>Bacterial Infections</topic><topic>Bacterial Infections - drug therapy</topic><topic>Bacterial Infections - microbiology</topic><topic>Biological and medical sciences</topic><topic>Drug Resistance, Multiple, Bacterial - drug effects</topic><topic>Enterococcus</topic><topic>Enterococcus - drug effects</topic><topic>Enterococcus - growth &amp; development</topic><topic>Escherichia coli</topic><topic>Escherichia coli - drug effects</topic><topic>Escherichia coli - growth &amp; development</topic><topic>Experimental Therapeutics</topic><topic>Gene Expression</topic><topic>Haemophilus influenzae</topic><topic>Haemophilus influenzae - drug effects</topic><topic>Haemophilus influenzae - growth &amp; development</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methicillin-Resistant Staphylococcus aureus</topic><topic>Methicillin-Resistant Staphylococcus aureus - drug effects</topic><topic>Methicillin-Resistant Staphylococcus aureus - growth &amp; development</topic><topic>Mice</topic><topic>Microbial Sensitivity Tests</topic><topic>Peritoneum - drug effects</topic><topic>Peritoneum - microbiology</topic><topic>Pharmacology. Drug treatments</topic><topic>Ribosomes - drug effects</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus aureus - drug effects</topic><topic>Staphylococcus aureus - growth &amp; development</topic><topic>Streptococcus pneumoniae</topic><topic>Streptococcus pneumoniae - drug effects</topic><topic>Streptococcus pneumoniae - growth &amp; development</topic><topic>Tetracyclines</topic><topic>Tetracyclines - chemical synthesis</topic><topic>Tetracyclines - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MACONE, A. B</creatorcontrib><creatorcontrib>CARUSO, B. K</creatorcontrib><creatorcontrib>LEAHY, R. G</creatorcontrib><creatorcontrib>DONATELLI, J</creatorcontrib><creatorcontrib>WEIR, S</creatorcontrib><creatorcontrib>DRAPER, M. P</creatorcontrib><creatorcontrib>TANAKA, S. K</creatorcontrib><creatorcontrib>LEVY, S. B</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Antimicrobial Agents and Chemotherapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MACONE, A. B</au><au>CARUSO, B. K</au><au>LEAHY, R. G</au><au>DONATELLI, J</au><au>WEIR, S</au><au>DRAPER, M. P</au><au>TANAKA, S. K</au><au>LEVY, S. B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2014-02-01</date><risdate>2014</risdate><volume>58</volume><issue>2</issue><spage>1127</spage><epage>1135</epage><pages>1127-1135</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions &amp; Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       </abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>24295985</pmid><doi>10.1128/AAC.01242-13</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0066-4804
ispartof Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.1127-1135
issn 0066-4804
1098-6596
language eng
recordid cdi_proquest_miscellaneous_1492720115
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Animals
Anti-Bacterial Agents
Anti-Bacterial Agents - chemical synthesis
Anti-Bacterial Agents - pharmacology
Antibiotics. Antiinfectious agents. Antiparasitic agents
ATP-Binding Cassette Transporters - antagonists & inhibitors
ATP-Binding Cassette Transporters - genetics
ATP-Binding Cassette Transporters - metabolism
Bacterial Infections
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Biological and medical sciences
Drug Resistance, Multiple, Bacterial - drug effects
Enterococcus
Enterococcus - drug effects
Enterococcus - growth & development
Escherichia coli
Escherichia coli - drug effects
Escherichia coli - growth & development
Experimental Therapeutics
Gene Expression
Haemophilus influenzae
Haemophilus influenzae - drug effects
Haemophilus influenzae - growth & development
Male
Medical sciences
Methicillin-Resistant Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus - drug effects
Methicillin-Resistant Staphylococcus aureus - growth & development
Mice
Microbial Sensitivity Tests
Peritoneum - drug effects
Peritoneum - microbiology
Pharmacology. Drug treatments
Ribosomes - drug effects
Staphylococcus aureus
Staphylococcus aureus - drug effects
Staphylococcus aureus - growth & development
Streptococcus pneumoniae
Streptococcus pneumoniae - drug effects
Streptococcus pneumoniae - growth & development
Tetracyclines
Tetracyclines - chemical synthesis
Tetracyclines - pharmacology
title In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T03%3A29%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pasca&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=In%20Vitro%20and%20In%20Vivo%20Antibacterial%20Activities%20of%20Omadacycline,%20a%20Novel%20Aminomethylcycline&rft.jtitle=Antimicrobial%20Agents%20and%20Chemotherapy&rft.au=MACONE,%20A.%20B&rft.date=2014-02-01&rft.volume=58&rft.issue=2&rft.spage=1127&rft.epage=1135&rft.pages=1127-1135&rft.issn=0066-4804&rft.eissn=1098-6596&rft.coden=AACHAX&rft_id=info:doi/10.1128/AAC.01242-13&rft_dat=%3Cproquest_pasca%3E1492720115%3C/proquest_pasca%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1492720115&rft_id=info:pmid/24295985&rfr_iscdi=true