In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2014-02, Vol.58 (2), p.1127-1135 |
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creator | MACONE, A. B CARUSO, B. K LEAHY, R. G DONATELLI, J WEIR, S DRAPER, M. P TANAKA, S. K LEVY, S. B |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.01242-13</identifier><identifier>PMID: 24295985</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject><![CDATA[Animals ; Anti-Bacterial Agents ; Anti-Bacterial Agents - chemical synthesis ; Anti-Bacterial Agents - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; ATP-Binding Cassette Transporters - antagonists & inhibitors ; ATP-Binding Cassette Transporters - genetics ; ATP-Binding Cassette Transporters - metabolism ; Bacterial Infections ; Bacterial Infections - drug therapy ; Bacterial Infections - microbiology ; Biological and medical sciences ; Drug Resistance, Multiple, Bacterial - drug effects ; Enterococcus ; Enterococcus - drug effects ; Enterococcus - growth & development ; Escherichia coli ; Escherichia coli - drug effects ; Escherichia coli - growth & development ; Experimental Therapeutics ; Gene Expression ; Haemophilus influenzae ; Haemophilus influenzae - drug effects ; Haemophilus influenzae - growth & development ; Male ; Medical sciences ; Methicillin-Resistant Staphylococcus aureus ; Methicillin-Resistant Staphylococcus aureus - drug effects ; Methicillin-Resistant Staphylococcus aureus - growth & development ; Mice ; Microbial Sensitivity Tests ; Peritoneum - drug effects ; Peritoneum - microbiology ; Pharmacology. Drug treatments ; Ribosomes - drug effects ; Staphylococcus aureus ; Staphylococcus aureus - drug effects ; Staphylococcus aureus - growth & development ; Streptococcus pneumoniae ; Streptococcus pneumoniae - drug effects ; Streptococcus pneumoniae - growth & development ; Tetracyclines ; Tetracyclines - chemical synthesis ; Tetracyclines - pharmacology]]></subject><ispartof>Antimicrobial Agents and Chemotherapy, 2014-02, Vol.58 (2), p.1127-1135</ispartof><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014, American Society for Microbiology. All Rights Reserved.</rights><rights>Copyright © 2014, American Society for Microbiology. All Rights Reserved. 2014 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</citedby><cites>FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910882/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910882/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28251665$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24295985$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>MACONE, A. B</creatorcontrib><creatorcontrib>CARUSO, B. K</creatorcontrib><creatorcontrib>LEAHY, R. G</creatorcontrib><creatorcontrib>DONATELLI, J</creatorcontrib><creatorcontrib>WEIR, S</creatorcontrib><creatorcontrib>DRAPER, M. P</creatorcontrib><creatorcontrib>TANAKA, S. K</creatorcontrib><creatorcontrib>LEVY, S. B</creatorcontrib><title>In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Animals</subject><subject>Anti-Bacterial Agents</subject><subject>Anti-Bacterial Agents - chemical synthesis</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>ATP-Binding Cassette Transporters - antagonists & inhibitors</subject><subject>ATP-Binding Cassette Transporters - genetics</subject><subject>ATP-Binding Cassette Transporters - metabolism</subject><subject>Bacterial Infections</subject><subject>Bacterial Infections - drug therapy</subject><subject>Bacterial Infections - microbiology</subject><subject>Biological and medical sciences</subject><subject>Drug Resistance, Multiple, Bacterial - drug effects</subject><subject>Enterococcus</subject><subject>Enterococcus - drug effects</subject><subject>Enterococcus - growth & development</subject><subject>Escherichia coli</subject><subject>Escherichia coli - drug effects</subject><subject>Escherichia coli - growth & development</subject><subject>Experimental Therapeutics</subject><subject>Gene Expression</subject><subject>Haemophilus influenzae</subject><subject>Haemophilus influenzae - drug effects</subject><subject>Haemophilus influenzae - growth & development</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methicillin-Resistant Staphylococcus aureus</subject><subject>Methicillin-Resistant Staphylococcus aureus - drug effects</subject><subject>Methicillin-Resistant Staphylococcus aureus - growth & development</subject><subject>Mice</subject><subject>Microbial Sensitivity Tests</subject><subject>Peritoneum - drug effects</subject><subject>Peritoneum - microbiology</subject><subject>Pharmacology. 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B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a517t-5698b3f11b4c0eb072e76233b73a34ba025e0ba867ab5387d96ee8cb9e4e14803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Animals</topic><topic>Anti-Bacterial Agents</topic><topic>Anti-Bacterial Agents - chemical synthesis</topic><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>ATP-Binding Cassette Transporters - antagonists & inhibitors</topic><topic>ATP-Binding Cassette Transporters - genetics</topic><topic>ATP-Binding Cassette Transporters - metabolism</topic><topic>Bacterial Infections</topic><topic>Bacterial Infections - drug therapy</topic><topic>Bacterial Infections - microbiology</topic><topic>Biological and medical sciences</topic><topic>Drug Resistance, Multiple, Bacterial - drug effects</topic><topic>Enterococcus</topic><topic>Enterococcus - drug effects</topic><topic>Enterococcus - growth & development</topic><topic>Escherichia coli</topic><topic>Escherichia coli - drug effects</topic><topic>Escherichia coli - growth & development</topic><topic>Experimental Therapeutics</topic><topic>Gene Expression</topic><topic>Haemophilus influenzae</topic><topic>Haemophilus influenzae - drug effects</topic><topic>Haemophilus influenzae - growth & development</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methicillin-Resistant Staphylococcus aureus</topic><topic>Methicillin-Resistant Staphylococcus aureus - drug effects</topic><topic>Methicillin-Resistant Staphylococcus aureus - growth & development</topic><topic>Mice</topic><topic>Microbial Sensitivity Tests</topic><topic>Peritoneum - drug effects</topic><topic>Peritoneum - microbiology</topic><topic>Pharmacology. Drug treatments</topic><topic>Ribosomes - drug effects</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus aureus - drug effects</topic><topic>Staphylococcus aureus - growth & development</topic><topic>Streptococcus pneumoniae</topic><topic>Streptococcus pneumoniae - drug effects</topic><topic>Streptococcus pneumoniae - growth & development</topic><topic>Tetracyclines</topic><topic>Tetracyclines - chemical synthesis</topic><topic>Tetracyclines - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MACONE, A. B</creatorcontrib><creatorcontrib>CARUSO, B. K</creatorcontrib><creatorcontrib>LEAHY, R. G</creatorcontrib><creatorcontrib>DONATELLI, J</creatorcontrib><creatorcontrib>WEIR, S</creatorcontrib><creatorcontrib>DRAPER, M. P</creatorcontrib><creatorcontrib>TANAKA, S. K</creatorcontrib><creatorcontrib>LEVY, S. 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B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline</atitle><jtitle>Antimicrobial Agents and Chemotherapy</jtitle><stitle>Antimicrob Agents Chemother</stitle><addtitle>Antimicrob Agents Chemother</addtitle><date>2014-02-01</date><risdate>2014</risdate><volume>58</volume><issue>2</issue><spage>1127</spage><epage>1135</epage><pages>1127-1135</pages><issn>0066-4804</issn><eissn>1098-6596</eissn><coden>AACHAX</coden><abstract>Classifications
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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>24295985</pmid><doi>10.1128/AAC.01242-13</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Animals Anti-Bacterial Agents Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents ATP-Binding Cassette Transporters - antagonists & inhibitors ATP-Binding Cassette Transporters - genetics ATP-Binding Cassette Transporters - metabolism Bacterial Infections Bacterial Infections - drug therapy Bacterial Infections - microbiology Biological and medical sciences Drug Resistance, Multiple, Bacterial - drug effects Enterococcus Enterococcus - drug effects Enterococcus - growth & development Escherichia coli Escherichia coli - drug effects Escherichia coli - growth & development Experimental Therapeutics Gene Expression Haemophilus influenzae Haemophilus influenzae - drug effects Haemophilus influenzae - growth & development Male Medical sciences Methicillin-Resistant Staphylococcus aureus Methicillin-Resistant Staphylococcus aureus - drug effects Methicillin-Resistant Staphylococcus aureus - growth & development Mice Microbial Sensitivity Tests Peritoneum - drug effects Peritoneum - microbiology Pharmacology. Drug treatments Ribosomes - drug effects Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - growth & development Streptococcus pneumoniae Streptococcus pneumoniae - drug effects Streptococcus pneumoniae - growth & development Tetracyclines Tetracyclines - chemical synthesis Tetracyclines - pharmacology |
title | In Vitro and In Vivo Antibacterial Activities of Omadacycline, a Novel Aminomethylcycline |
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