Vasculitis resulting from a superficial femoral artery angioplasty with a paclitaxel-eluting balloon

Drug-eluting balloons (DEBs) coated with the antiproliferative agent paclitaxel may improve primary patency by reducing recurrent luminal stenosis. A proportion of the active drug and excipient coating are known to embolize distally, but until now, there have been no reports of adverse events result...

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Veröffentlicht in:Journal of vascular surgery 2014-02, Vol.59 (2), p.520-523
Hauptverfasser: Thomas, Shannon D., FRACS, McDonald, Robert R.A., FACD, Varcoe, Ramon L., MS, FRACS
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container_end_page 523
container_issue 2
container_start_page 520
container_title Journal of vascular surgery
container_volume 59
creator Thomas, Shannon D., FRACS
McDonald, Robert R.A., FACD
Varcoe, Ramon L., MS, FRACS
description Drug-eluting balloons (DEBs) coated with the antiproliferative agent paclitaxel may improve primary patency by reducing recurrent luminal stenosis. A proportion of the active drug and excipient coating are known to embolize distally, but until now, there have been no reports of adverse events resulting from their use. We report an unusual case of a painful nodular, biopsy specimen-proven vasculitic rash that afflicted the ipsilateral lower limb of a patient after superficial femoral artery treatment with a DEB. This adverse event may have implications for the use of DEB in this and other vascular territories.
doi_str_mv 10.1016/j.jvs.2013.03.013
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source MEDLINE; Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals
subjects Aged
Angioplasty, Balloon - adverse effects
Angioplasty, Balloon - instrumentation
Biopsy
Cardiovascular Agents - administration & dosage
Coated Materials, Biocompatible
Female
Femoral Artery - physiopathology
Humans
Intermittent Claudication - diagnosis
Intermittent Claudication - physiopathology
Intermittent Claudication - therapy
Paclitaxel - administration & dosage
Surgery
Treatment Outcome
Vascular Access Devices
Vascular Patency
Vasculitis - diagnosis
Vasculitis - etiology
Vasculitis - therapy
title Vasculitis resulting from a superficial femoral artery angioplasty with a paclitaxel-eluting balloon
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