Downregulation of miR‐15a due to LMP1 promotes cell proliferation and predicts poor prognosis in nasal NK/T‐cell lymphoma

Nasal NK/T‐cell lymphoma (NNKTL) is an Epstein‐Barr virus (EBV)‐associated malignancy and has distinct clinical and histological features. However, its genetic features are hitherto unclear. MicroRNAs (miRNAs) play a crucial role in the pathogenesis of several malignancies via regulating gene expres...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of hematology 2014-01, Vol.89 (1), p.25-33
Hauptverfasser:	Komabayashi, Yuki, Kishibe, Kan, Nagato, Toshihiro, Ueda, Seigo, Takahara, Miki, Harabuchi, Yasuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Cell Cycle Checkpoints - genetics Cell Line, Tumor Cell Proliferation Cyclin D1 - genetics Cyclin D1 - metabolism Down-Regulation Female Gene Expression Regulation, Neoplastic Hematology Humans Lymphoma, Extranodal NK-T-Cell - genetics Lymphoma, Extranodal NK-T-Cell - mortality Lymphoma, Extranodal NK-T-Cell - pathology Male MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Neoplasm Staging Oncogene Proteins v-myb - genetics Oncogene Proteins v-myb - metabolism Prognosis Viral Matrix Proteins - genetics Viral Matrix Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!