Silencing of LASS2/TMSG1 enhances invasion and metastasis capacity of prostate cancer cell

ABSTRACT Homo sapiens longevity assurance homolog 2 of yeast LAG1 (LASS2), also known as tumor metastasis suppressor gene 1 (TMSG1), was firstly cloned by our laboratory in 1999. However, its antitumor molecular mechanisms are still unclear. LASS2/TMSG‐1 could directly interact with the C subunit of...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular biochemistry 2014-04, Vol.115 (4), p.731-743
Hauptverfasser:	Xu, Xiaoyan, Liu, Beiying, Zou, Pengcheng, Zhang, Yan, You, Jiangfeng, Pei, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Apoptosis - genetics Base Sequence Cell Cycle - drug effects Cell Cycle - genetics Cell Line, Tumor Gene Silencing Humans LASS2/TMSG1 Male Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Membrane Proteins - genetics Mice Mice, Nude Molecular Sequence Data Neoplasm Invasiveness - genetics PC-3M-2B4 CELLS PROSTATE CARCINOMA Prostatic Neoplasms - genetics Prostatic Neoplasms - pathology RNA, Small Interfering - genetics shRNA Sphingosine N-Acyltransferase - genetics Tumor Suppressor Proteins - genetics VACUOLAR H+ ATPase Vacuolar Proton-Translocating ATPases - metabolism Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!