Recurrent Immune Reconstitution Inflammatory Syndrome of Tuberculous Brain Infection in People Living with HIV/AIDS: A Case Report
HIV infection has changed the scenario of infectious disease. HIV-associated immunodeficiency resulted in a wide spectrum of new opportunistic infections. After introduction of antiretroviral therapy (ART), immune reconstitution inflammatory syndrome (IRIS) became an important challenge in managemen...
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| Veröffentlicht in: | Journal of the International Association of Providers of AIDS Care 2014-01, Vol.13 (1), p.15-17 |
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| container_title | Journal of the International Association of Providers of AIDS Care |
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| creator | Krishnaraj, Raja Chokkalingam, Chandrasekar Krishnarajasekhar, O. R. Narayanan, Ravichandran Sadagopan, Kumar Ayyamperumal, Mahilmaran |
| description | HIV infection has changed the scenario of infectious disease. HIV-associated immunodeficiency resulted in a wide spectrum of new opportunistic infections. After introduction of antiretroviral therapy (ART), immune reconstitution inflammatory syndrome (IRIS) became an important challenge in management of 10% to 25% of the patients. Meta-analyses of IRIS from various reports published worldwide by Monika Muller et al described 12% IRIS incidence and 15.7% IRIS tuberculosis. Among IRIS tuberculosis, central nervous system involvement with IRIS tuberculous meningitis forms only 7%. Only 9 cases of tuberculous brain abscess is reported in patients with AIDS so far. The IRIS tuberculous brain abscess is very rare, and so far only 1 case is reported as a paradoxical reaction after ART initiation. Here, we report a case of recurrent IRIS tuberculosis meningitis and brain abscess. |
| doi_str_mv | 10.1177/2325957413488170 |
| format | Article |
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The IRIS tuberculous brain abscess is very rare, and so far only 1 case is reported as a paradoxical reaction after ART initiation. 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Among IRIS tuberculosis, central nervous system involvement with IRIS tuberculous meningitis forms only 7%. Only 9 cases of tuberculous brain abscess is reported in patients with AIDS so far. The IRIS tuberculous brain abscess is very rare, and so far only 1 case is reported as a paradoxical reaction after ART initiation. 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| source | Sage Journals GOLD Open Access 2024 |
| subjects | Acquired Immunodeficiency Syndrome - immunology Acquired Immunodeficiency Syndrome - microbiology Adult AIDS-Related Opportunistic Infections - immunology AIDS-Related Opportunistic Infections - microbiology AIDS-Related Opportunistic Infections - virology Anti-Retroviral Agents - therapeutic use Antitubercular Agents - therapeutic use HIV Infections - immunology HIV Infections - microbiology Humans Immune Reconstitution Inflammatory Syndrome - microbiology Immune Reconstitution Inflammatory Syndrome - virology Male Tomography, X-Ray Computed Tuberculoma, Intracranial - immunology Tuberculoma, Intracranial - virology |
| title | Recurrent Immune Reconstitution Inflammatory Syndrome of Tuberculous Brain Infection in People Living with HIV/AIDS: A Case Report |
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