Probucol combined with valsartan in immunoglobulin A nephropathy: A multi-centre, open labelled, randomized controlled study

Aim Angiotensin receptor antagonists (ARBs) and anti‐oxidants reduce urinary protein excretion and delay progression of immunoglobulin A (IgA) nephropathy. We investigated the efficacy and safety of probucol (an anti‐oxidant) combined with valsartan (an ARB) on the progression of IgA nephropathy. Me...

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Veröffentlicht in:	Nephrology (Carlton, Vic.) Vic.), 2014-01, Vol.19 (1), p.40-46
Hauptverfasser:	Ye, Zhiming, Zhang, Li, Xu, Lixia, Shi, Wei, Hu, Haitang, Shi, Xiaofeng, Zhong, Weiqiang, Hou, Shuan, Yan, Honghong, Zhang, Bin, Xia, Yunfeng, Wang, Wenjian, Feng, Zonglin, Wang, Liping, Liang, Yongzheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angiotensin II Type 1 Receptor Blockers - administration & dosage anti-oxidation Antioxidants - administration & dosage Drug Therapy, Combination Female Glomerulonephritis, IGA - drug therapy Glomerulonephritis, IGA - mortality Glomerulonephritis, IGA - physiopathology Humans IgA nephropathy Male Middle Aged probucol Probucol - administration & dosage Probucol - adverse effects randomized controlled study Tetrazoles - administration & dosage Tetrazoles - adverse effects Valine - administration & dosage Valine - adverse effects Valine - analogs & derivatives Valsartan
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