Assessment of an automated in vitro basal cytotoxicity test system based on metabolically-competent cells

► In vitro hepatotoxicity testing. ► HepaRG, non-proliferating undifferentiated HepaRG, proliferative HepG2. ► Detoxification, bio-activation, inhibition of proliferation. ► Automated viability assay. When in vitro test systems are evaluated for assessment of the toxicity of chemical compounds, part...

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Veröffentlicht in:	Toxicology in vitro 2013-03, Vol.27 (2), p.760-767
Hauptverfasser:	Rodrigues, Robim M., Bouhifd, Mounir, Bories, Gilles, Sacco, Maria-Grazia, Gribaldo, Laura, Fabbri, Marco, Coecke, Sandra, Whelan, Maurice P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Automation Basal cytotoxicity Cell Line Cell Survival - drug effects Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Hep G2 Cells HepaRG HepG2 Humans In vitro test system Neutral Red - metabolism NRU Toxicity Tests - methods
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