Culture medium type affects endocytosis of multi-walled carbon nanotubes in BEAS-2B cells and subsequent biological response

•The differentiation of BEAS-2B cell by serum affects CNT uptake and the bioresponses.•CNT uptake of BEAS-2B cell by serum is reversible.•BEAS-2B cells with serum show bioresponses that are very similar to those of HBEpCs.•MWCNT uptake was suppressed by endocytosis inhibitors in BEAS-2B cells and HB...

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Veröffentlicht in:	Toxicology in vitro 2013-09, Vol.27 (6), p.1679-1685
Hauptverfasser:	Haniu, Hisao, Saito, Naoto, Matsuda, Yoshikazu, Tsukahara, Tamotsu, Maruyama, Kayo, Usui, Yuki, Aoki, Kaoru, Takanashi, Seiji, Kobayashi, Shinsuke, Nomura, Hiroki, Okamoto, Masanori, Shimizu, Masayuki, Kato, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	BEAS-2B cells Bronchi - cytology Cell Culture Techniques - methods Cell Line Cell Survival - drug effects Cells, Cultured Culture Media Cytokines - metabolism Cytotoxicity Endocytosis Epithelial Cells - drug effects Epithelial Cells - metabolism Humans Multi-walled carbon nanotube Nanotubes, Carbon - toxicity Normal human bronchial epithelial cells Serum
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