Effect of Wheat Germ Agglutinin on T Lymphocyte Activation

Wheat germ agglutinin (WGA) is low mitogenic or nonmitogenic for human T lymphocytes and inhibits phytohemagglutinin (PHA)-induced mitotic response of the lymphocytes. In this study, the effect of WGA was analyzed in terms of interleukin 2 (IL2) production, expression of IL2 receptor, and IL2 respon...

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Veröffentlicht in:	MICROBIOLOGY and IMMUNOLOGY 1988, Vol.32(4), pp.413-422
Hauptverfasser:	Kawakami, Kazuyoshi, Yamamoto, Yusei, Onoue, Kaoru
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcium - metabolism Calmodulin - antagonists & inhibitors Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Immunological reactions in vitro Interleukin-2 - analysis Interleukin-2 - biosynthesis Lymphoblastic transformation (stimulation by antigen, mitogen, mixed lymphocyte reactions) Lymphocyte Activation Palatine Tonsil - cytology Phytohemagglutinins - pharmacology Protein Kinase C - antagonists & inhibitors Receptors, Immunologic - metabolism Receptors, Interleukin-2 RNA, Messenger - biosynthesis T-Lymphocytes - analysis T-Lymphocytes - immunology T-Lymphocytes - metabolism Tetradecanoylphorbol Acetate - pharmacology Wheat Germ Agglutinins - antagonists & inhibitors Wheat Germ Agglutinins - pharmacology
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