A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum: e79059

Resistance to the cytostatic activity of the antimalarial drug chloroquine (CQ) is becoming well understood, however, resistance to cytocidal effects of CQ is largely unexplored. We find that PfCRT mutations that almost fully recapitulate P. falciparum cytostatic CQ resistance (CQRCS) as quantified...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11)
Hauptverfasser:	Gaviria, David, Paguio, Michelle F, Turnbull, Lindsey B, Tan, Asako, Siriwardana, Amila, Ghosh, Debasish, Ferdig, Michael T, Sinai, Anthony P, Roepe, Paul D
Format:	Artikel
Sprache:	eng
Schlagworte:	Plasmodium falciparum
Online-Zugang:	Volltext
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