Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: A 24-wk, randomized control trial

Abstract Objective The aim of this study was to evaluate the effects of pistachio nuts as an adjunct to diet and exercise on body composition, metabolic, inflammatory, and oxidative stress parameters in Asian Indians with metabolic syndrome. Methods In this 24-wk randomized control trial, 60 individ...

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Veröffentlicht in:Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2014-02, Vol.30 (2), p.192-197
Hauptverfasser: Gulati, Seema, Ph.D, Misra, Anoop, M.D, Pandey, Ravindra Mohan, Ph.D, Bhatt, Surya Prakash, Ph.D, Saluja, Shelza, M.B.B.S
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container_issue 2
container_start_page 192
container_title Nutrition (Burbank, Los Angeles County, Calif.)
container_volume 30
creator Gulati, Seema, Ph.D
Misra, Anoop, M.D
Pandey, Ravindra Mohan, Ph.D
Bhatt, Surya Prakash, Ph.D
Saluja, Shelza, M.B.B.S
description Abstract Objective The aim of this study was to evaluate the effects of pistachio nuts as an adjunct to diet and exercise on body composition, metabolic, inflammatory, and oxidative stress parameters in Asian Indians with metabolic syndrome. Methods In this 24-wk randomized control trial, 60 individuals with the metabolic syndrome were randomized to either pistachio (intervention group) or control group (diet as per weight and physical activity profile, modulated according to dietary guidelines for Asian Indians) after 3 wk of a diet and exercise run in. In the first group, unsalted pistachios (20% energy) were given daily. A standard diet and exercise protocol was followed for both groups. Body weight, waist circumference (WC), magnetic resonance imaging estimation of intraabdominal adipose tissue and subcutaneous abdominal adipose tissue, fasting blood glucose (FBG), fasting serum insulin, glycosylated hemoglobin, lipid profile, high-sensitivity C-reactive protein (hs-CRP), adiponectin, free fatty acids (FFAs), tumor necrosis factor (TNF)-α, leptin, and thiobarbituric acid reactive substances (TBARS) were assessed before and after the intervention. Results Statistically significant improvement in mean values for various parameters in the intervention group compared with control group were as follows: WC ( P < 0.02), FBG ( P < 0.04), total cholesterol ( P < 0.02), low-density lipoprotein cholesterol ( P < 0.006), hs-CRP ( P < 0.05), TNF-α ( P < 0.03), FFAs ( P < 0.001), TBARS ( P < 0.01), and adiponectin levels ( P < 0.001). Conclusion A single food intervention with pistachios leads to beneficial effects on the cardiometabolic profile of Asian Indians with metabolic syndrome.
doi_str_mv 10.1016/j.nut.2013.08.005
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Methods In this 24-wk randomized control trial, 60 individuals with the metabolic syndrome were randomized to either pistachio (intervention group) or control group (diet as per weight and physical activity profile, modulated according to dietary guidelines for Asian Indians) after 3 wk of a diet and exercise run in. In the first group, unsalted pistachios (20% energy) were given daily. A standard diet and exercise protocol was followed for both groups. Body weight, waist circumference (WC), magnetic resonance imaging estimation of intraabdominal adipose tissue and subcutaneous abdominal adipose tissue, fasting blood glucose (FBG), fasting serum insulin, glycosylated hemoglobin, lipid profile, high-sensitivity C-reactive protein (hs-CRP), adiponectin, free fatty acids (FFAs), tumor necrosis factor (TNF)-α, leptin, and thiobarbituric acid reactive substances (TBARS) were assessed before and after the intervention. Results Statistically significant improvement in mean values for various parameters in the intervention group compared with control group were as follows: WC ( P < 0.02), FBG ( P < 0.04), total cholesterol ( P < 0.02), low-density lipoprotein cholesterol ( P < 0.006), hs-CRP ( P < 0.05), TNF-α ( P < 0.03), FFAs ( P < 0.001), TBARS ( P < 0.01), and adiponectin levels ( P < 0.001). Conclusion A single food intervention with pistachios leads to beneficial effects on the cardiometabolic profile of Asian Indians with metabolic syndrome.]]></description><identifier>ISSN: 0899-9007</identifier><identifier>EISSN: 1873-1244</identifier><identifier>DOI: 10.1016/j.nut.2013.08.005</identifier><identifier>PMID: 24377454</identifier><identifier>CODEN: NUTRER</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Abdomen ; Adiponectin - blood ; Adipose tissue ; Adiposity ; Adult ; Asian Continental Ancestry Group ; Biological and medical sciences ; Blood Glucose - metabolism ; Body Composition ; Body Weight ; C-Reactive Protein - metabolism ; Carbohydrates ; Cardiovascular disease ; Cholesterol ; Cholesterol, LDL - blood ; Compliance ; Confidence intervals ; Diabetes ; Diet ; Exercise ; Fasting ; Fatty acids ; Fatty Acids - blood ; Feeding. Feeding behavior ; Female ; Fundamental and applied biological sciences. Psychology ; Gastroenterology and Hepatology ; Glucose ; Hemoglobins - metabolism ; Humans ; Hyperglycemia ; Hypertension ; Insulin - blood ; Leptin - blood ; Lipids ; Lipoproteins ; Male ; Medical sciences ; Metabolic diseases ; Metabolic disorders ; Metabolic syndrome ; Metabolic Syndrome - blood ; Metabolic Syndrome - diet therapy ; Middle Aged ; Miscellaneous ; NMR ; Nuclear magnetic resonance ; Nutrition research ; Nuts - chemistry ; Obesity ; Other metabolic disorders ; Oxidative stress ; Oxidative Stress - physiology ; Patient Compliance ; Pistachio nut ; Pistacia - chemistry ; Proteins ; Risk factors ; Thiobarbituric Acid Reactive Substances - metabolism ; Tumor Necrosis Factor-alpha - blood ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>Nutrition (Burbank, Los Angeles County, Calif.), 2014-02, Vol.30 (2), p.192-197</ispartof><rights>Elsevier Inc.</rights><rights>2014 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Feb 2014</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c499t-2c6c21d0edddbd71eed64ca517fa6439b5a7aa8efc34f1c990a71e5f75b6f2ff3</citedby><cites>FETCH-LOGICAL-c499t-2c6c21d0edddbd71eed64ca517fa6439b5a7aa8efc34f1c990a71e5f75b6f2ff3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0899900713003833$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=28409374$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24377454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gulati, Seema, Ph.D</creatorcontrib><creatorcontrib>Misra, Anoop, M.D</creatorcontrib><creatorcontrib>Pandey, Ravindra Mohan, Ph.D</creatorcontrib><creatorcontrib>Bhatt, Surya Prakash, Ph.D</creatorcontrib><creatorcontrib>Saluja, Shelza, M.B.B.S</creatorcontrib><title>Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: A 24-wk, randomized control trial</title><title>Nutrition (Burbank, Los Angeles County, Calif.)</title><addtitle>Nutrition</addtitle><description><![CDATA[Abstract Objective The aim of this study was to evaluate the effects of pistachio nuts as an adjunct to diet and exercise on body composition, metabolic, inflammatory, and oxidative stress parameters in Asian Indians with metabolic syndrome. Methods In this 24-wk randomized control trial, 60 individuals with the metabolic syndrome were randomized to either pistachio (intervention group) or control group (diet as per weight and physical activity profile, modulated according to dietary guidelines for Asian Indians) after 3 wk of a diet and exercise run in. In the first group, unsalted pistachios (20% energy) were given daily. A standard diet and exercise protocol was followed for both groups. Body weight, waist circumference (WC), magnetic resonance imaging estimation of intraabdominal adipose tissue and subcutaneous abdominal adipose tissue, fasting blood glucose (FBG), fasting serum insulin, glycosylated hemoglobin, lipid profile, high-sensitivity C-reactive protein (hs-CRP), adiponectin, free fatty acids (FFAs), tumor necrosis factor (TNF)-α, leptin, and thiobarbituric acid reactive substances (TBARS) were assessed before and after the intervention. Results Statistically significant improvement in mean values for various parameters in the intervention group compared with control group were as follows: WC ( P < 0.02), FBG ( P < 0.04), total cholesterol ( P < 0.02), low-density lipoprotein cholesterol ( P < 0.006), hs-CRP ( P < 0.05), TNF-α ( P < 0.03), FFAs ( P < 0.001), TBARS ( P < 0.01), and adiponectin levels ( P < 0.001). Conclusion A single food intervention with pistachios leads to beneficial effects on the cardiometabolic profile of Asian Indians with metabolic syndrome.]]></description><subject>Abdomen</subject><subject>Adiponectin - blood</subject><subject>Adipose tissue</subject><subject>Adiposity</subject><subject>Adult</subject><subject>Asian Continental Ancestry Group</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Body Composition</subject><subject>Body Weight</subject><subject>C-Reactive Protein - metabolism</subject><subject>Carbohydrates</subject><subject>Cardiovascular disease</subject><subject>Cholesterol</subject><subject>Cholesterol, LDL - blood</subject><subject>Compliance</subject><subject>Confidence intervals</subject><subject>Diabetes</subject><subject>Diet</subject><subject>Exercise</subject><subject>Fasting</subject><subject>Fatty acids</subject><subject>Fatty Acids - blood</subject><subject>Feeding. 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Psychology</subject><subject>Gastroenterology and Hepatology</subject><subject>Glucose</subject><subject>Hemoglobins - metabolism</subject><subject>Humans</subject><subject>Hyperglycemia</subject><subject>Hypertension</subject><subject>Insulin - blood</subject><subject>Leptin - blood</subject><subject>Lipids</subject><subject>Lipoproteins</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metabolic diseases</subject><subject>Metabolic disorders</subject><subject>Metabolic syndrome</subject><subject>Metabolic Syndrome - blood</subject><subject>Metabolic Syndrome - diet therapy</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Nutrition research</subject><subject>Nuts - chemistry</subject><subject>Obesity</subject><subject>Other metabolic disorders</subject><subject>Oxidative stress</subject><subject>Oxidative Stress - physiology</subject><subject>Patient Compliance</subject><subject>Pistachio nut</subject><subject>Pistacia - chemistry</subject><subject>Proteins</subject><subject>Risk factors</subject><subject>Thiobarbituric Acid Reactive Substances - metabolism</subject><subject>Tumor Necrosis Factor-alpha - blood</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0899-9007</issn><issn>1873-1244</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNktuKFDEQhhtR3HX1AbyRgAheTI859SEKwrCsurDghXod0jmwme1OxlRm1_GxfELTzOjAXohXBeH7_1TVX1X1nOAlwaR9s16GbV5STNgS90uMmwfVKek7VhPK-cPqFPdC1ALj7qR6ArDGGBPRisfVCeWs63jDT6tfF85ZnQFFhzYestLXPqJiW14CGqLZIR2nTQSffQwLNNmshjh6vUA-uFFNk8ox7ZAKBsUf3qjsby2CnCwA2qikisAmKDBagVcBXQZTCqA7n6-Pbgh2waQ42bdohSiv724WKBXPOPmf1pQWQk5xRDl5NT6tHjk1gn12qGfVtw8XX88_1VefP16er65qzYXINdWtpsRga4wZTEesNS3XqiGdUy1nYmhUp1RvnWbcES0EVgVqXNcMraPOsbPq9d53k-L3rYUsJw_ajqMKNm5BEi5oy2jD6f-guOup4F1BX95D13GbQhmkUF1DqGjZTJE9pVMESNbJTfKTSjtJsJyzl2tZQpJz9hL3smRfNC8Oztthsuav4k_YBXh1ABRoNbqyYO3hyPUcC9bN3Ls9Z8t2b71NErS3QVvjU7kVaaL_Zxvv76n16IMvH97YnYXjtBKoxPLLfKTzjRKGMesZY78BhR7kmQ</recordid><startdate>20140201</startdate><enddate>20140201</enddate><creator>Gulati, Seema, Ph.D</creator><creator>Misra, Anoop, M.D</creator><creator>Pandey, Ravindra Mohan, Ph.D</creator><creator>Bhatt, Surya Prakash, Ph.D</creator><creator>Saluja, Shelza, M.B.B.S</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7TS</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20140201</creationdate><title>Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: A 24-wk, randomized control trial</title><author>Gulati, Seema, Ph.D ; Misra, Anoop, M.D ; Pandey, Ravindra Mohan, Ph.D ; Bhatt, Surya Prakash, Ph.D ; Saluja, Shelza, M.B.B.S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c499t-2c6c21d0edddbd71eed64ca517fa6439b5a7aa8efc34f1c990a71e5f75b6f2ff3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Abdomen</topic><topic>Adiponectin - blood</topic><topic>Adipose tissue</topic><topic>Adiposity</topic><topic>Adult</topic><topic>Asian Continental Ancestry Group</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - metabolism</topic><topic>Body Composition</topic><topic>Body Weight</topic><topic>C-Reactive Protein - metabolism</topic><topic>Carbohydrates</topic><topic>Cardiovascular disease</topic><topic>Cholesterol</topic><topic>Cholesterol, LDL - blood</topic><topic>Compliance</topic><topic>Confidence intervals</topic><topic>Diabetes</topic><topic>Diet</topic><topic>Exercise</topic><topic>Fasting</topic><topic>Fatty acids</topic><topic>Fatty Acids - blood</topic><topic>Feeding. Feeding behavior</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gastroenterology and Hepatology</topic><topic>Glucose</topic><topic>Hemoglobins - metabolism</topic><topic>Humans</topic><topic>Hyperglycemia</topic><topic>Hypertension</topic><topic>Insulin - blood</topic><topic>Leptin - blood</topic><topic>Lipids</topic><topic>Lipoproteins</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Metabolic diseases</topic><topic>Metabolic disorders</topic><topic>Metabolic syndrome</topic><topic>Metabolic Syndrome - blood</topic><topic>Metabolic Syndrome - diet therapy</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Nutrition research</topic><topic>Nuts - chemistry</topic><topic>Obesity</topic><topic>Other metabolic disorders</topic><topic>Oxidative stress</topic><topic>Oxidative Stress - physiology</topic><topic>Patient Compliance</topic><topic>Pistachio nut</topic><topic>Pistacia - chemistry</topic><topic>Proteins</topic><topic>Risk factors</topic><topic>Thiobarbituric Acid Reactive Substances - metabolism</topic><topic>Tumor Necrosis Factor-alpha - blood</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gulati, Seema, Ph.D</creatorcontrib><creatorcontrib>Misra, Anoop, M.D</creatorcontrib><creatorcontrib>Pandey, Ravindra Mohan, Ph.D</creatorcontrib><creatorcontrib>Bhatt, Surya Prakash, Ph.D</creatorcontrib><creatorcontrib>Saluja, Shelza, M.B.B.S</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Career &amp; 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Methods In this 24-wk randomized control trial, 60 individuals with the metabolic syndrome were randomized to either pistachio (intervention group) or control group (diet as per weight and physical activity profile, modulated according to dietary guidelines for Asian Indians) after 3 wk of a diet and exercise run in. In the first group, unsalted pistachios (20% energy) were given daily. A standard diet and exercise protocol was followed for both groups. Body weight, waist circumference (WC), magnetic resonance imaging estimation of intraabdominal adipose tissue and subcutaneous abdominal adipose tissue, fasting blood glucose (FBG), fasting serum insulin, glycosylated hemoglobin, lipid profile, high-sensitivity C-reactive protein (hs-CRP), adiponectin, free fatty acids (FFAs), tumor necrosis factor (TNF)-α, leptin, and thiobarbituric acid reactive substances (TBARS) were assessed before and after the intervention. Results Statistically significant improvement in mean values for various parameters in the intervention group compared with control group were as follows: WC ( P < 0.02), FBG ( P < 0.04), total cholesterol ( P < 0.02), low-density lipoprotein cholesterol ( P < 0.006), hs-CRP ( P < 0.05), TNF-α ( P < 0.03), FFAs ( P < 0.001), TBARS ( P < 0.01), and adiponectin levels ( P < 0.001). Conclusion A single food intervention with pistachios leads to beneficial effects on the cardiometabolic profile of Asian Indians with metabolic syndrome.]]></abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>24377454</pmid><doi>10.1016/j.nut.2013.08.005</doi><tpages>6</tpages></addata></record>
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identifier ISSN: 0899-9007
ispartof Nutrition (Burbank, Los Angeles County, Calif.), 2014-02, Vol.30 (2), p.192-197
issn 0899-9007
1873-1244
language eng
recordid cdi_proquest_miscellaneous_1492632542
source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Abdomen
Adiponectin - blood
Adipose tissue
Adiposity
Adult
Asian Continental Ancestry Group
Biological and medical sciences
Blood Glucose - metabolism
Body Composition
Body Weight
C-Reactive Protein - metabolism
Carbohydrates
Cardiovascular disease
Cholesterol
Cholesterol, LDL - blood
Compliance
Confidence intervals
Diabetes
Diet
Exercise
Fasting
Fatty acids
Fatty Acids - blood
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gastroenterology and Hepatology
Glucose
Hemoglobins - metabolism
Humans
Hyperglycemia
Hypertension
Insulin - blood
Leptin - blood
Lipids
Lipoproteins
Male
Medical sciences
Metabolic diseases
Metabolic disorders
Metabolic syndrome
Metabolic Syndrome - blood
Metabolic Syndrome - diet therapy
Middle Aged
Miscellaneous
NMR
Nuclear magnetic resonance
Nutrition research
Nuts - chemistry
Obesity
Other metabolic disorders
Oxidative stress
Oxidative Stress - physiology
Patient Compliance
Pistachio nut
Pistacia - chemistry
Proteins
Risk factors
Thiobarbituric Acid Reactive Substances - metabolism
Tumor Necrosis Factor-alpha - blood
Vertebrates: anatomy and physiology, studies on body, several organs or systems
title Effects of pistachio nuts on body composition, metabolic, inflammatory and oxidative stress parameters in Asian Indians with metabolic syndrome: A 24-wk, randomized control trial
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