Association of common gene variants in vitamin D modulating genes and colon cancer recurrence

Purpose Low concentrations of 25-hydroxyvitamin D3 (25(OH)D) have been associated with increased risk and poor prognosis of various cancer types, including colon cancer. Common genetic variants in genes that influence circulating 25(OH)D levels may affect vitamin D concentrations and risk of vitamin...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2013-09, Vol.139 (9), p.1457-1464
Hauptverfasser:	Szkandera, Joanna, Absenger, Gudrun, Pichler, Martin, Stotz, Michael, Langsenlehner, Tanja, Samonigg, Hellmut, Renner, Wilfried, Gerger, Armin
Format:	Artikel
Sprache:	eng
Schlagworte:	7-Dehydrocholesterol reductase Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - genetics Cancer Research Cholestanetriol 26-Monooxygenase - genetics Colonic Neoplasms - genetics Colonic Neoplasms - pathology Colonic Neoplasms - therapy Colorectal cancer Cytochrome P450 Family 2 DNA, Neoplasm - genetics Female Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Genes Hematology Humans Internal Medicine Male Medical prognosis Medical sciences Medicine Medicine & Public Health Middle Aged Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasm Grading Neoplasm Recurrence, Local - diagnosis Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - therapy Neoplasm Staging Oncology Original Paper Oxidoreductases Acting on CH-CH Group Donors - genetics Pharmacology. Drug treatments Polymerase Chain Reaction Polymorphism, Single Nucleotide - genetics Prognosis Retrospective Studies Risk factors Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Time Factors Tumors Viral Envelope Proteins - genetics Vitamin D Vitamin D - metabolism
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