Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire: e80108

Transgenic chickens expressing human sequence antibodies would be a powerful tool to access human targets and epitopes that have been intractable in mammalian hosts because of tolerance to conserved proteins. To foster the development of the chicken platform, it is beneficial to validate transgene c...

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Veröffentlicht in:	PloS one 2013-11, Vol.8 (11)
Hauptverfasser:	Schusser, Benjamin, Yi, Henry, Collarini, Ellen J, Izquierdo, Shelley Mettler, Harriman, William D, Etches, Robert J, Leighton, Philip A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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