Exercise preconditioning modulates genotoxicity induced by doxorubicin in multiple organs of rats

The aim of this study was to investigate the effects of exercise in multiple organs of rats treated with doxorubicin. Male adult Wistar rats were distributed into the following groups: sedentary + NaCl; exercise + NaCl; sedentary + doxorubicin; and exercise + doxorubicin. Animals were sacrificed 2 d...

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Veröffentlicht in:	Cell biochemistry and function 2012-06, Vol.30 (4), p.293-296
Hauptverfasser:	Martins, Renato Almeida, Minari, André Luis, Chaves, Marcelo Donizetti, Santos, Ronaldo Wagner Thomatieli dos, Barbisan, Luis Fernando, Ribeiro, Daniel Araki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Comet Assay DNA damage DNA Damage - drug effects doxorubicin Doxorubicin - toxicity exercise Heart - drug effects Kidney - drug effects Liver - drug effects Male Physical Conditioning, Animal Rats Rats, Wistar single-cell gel (comet) assay
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