The chlamydial OTU domain‐containing protein ChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52

Summary Chlamydia are obligate intracellular pathogens. Upon contact with the host, they use type III secretion to deliver proteins into the cell, thereby triggering actin‐dependent entry and establishing the infection. We observed that Chlamydia caviae elicited a local and transient accumulation of...

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Veröffentlicht in:	Cellular microbiology 2013-12, Vol.15 (12), p.2064-2079
Hauptverfasser:	Furtado, Ana Rita, Essid, Miriam, Perrinet, Stéphanie, Balañá, María Eugenia, Yoder, Nicholas, Dehoux, Pierre, Subtil, Agathe
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacterial Proteins - metabolism Bacterial Secretion Systems Cell Line Chlamydia - metabolism Chlamydia Infections - microbiology Chlamydia Infections - transmission Chlamydophila pneumoniae HEK293 Cells HeLa Cells Humans Nuclear Proteins - metabolism Protein Binding Proteins RNA Interference RNA, Small Interfering Ubiquitin - metabolism Ubiquitin-Specific Proteases - metabolism
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