CD8 T-Cell Activation Is Associated With Lipodystrophy and Visceral Fat Accumulation in Antiretroviral Therapy–Treated Virologically Suppressed HIV-Infected Patients

OBJECTIVE:HIV-infected patients receiving antiretroviral treatment frequently accumulate fat at the abdominal level. It is unknown whether T-cell activation and immune phenotypes are associated with fat accumulation. Thus, the aim of the study was to search for an association between the presence of...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2013-12, Vol.64 (4), p.360-366
Hauptverfasser:	Guaraldi, Giovanni, Luzi, Kety, Bellistrì, Giusi Maria, Zona, Stefano, Domingues da Silva, Ana Rita, Bai, Francesca, Garlassi, Elisa, Marchetti, Giulia, Capeau, Jacqueline, Monforte, Antonella d’Arminio
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adipose Tissue Adult AIDS/HIV Anti-HIV Agents - therapeutic use Antiretroviral drugs Biological and medical sciences CD8-Positive T-Lymphocytes - physiology Cross-Sectional Studies Female Fundamental and applied biological sciences. Psychology HIV HIV Infections - drug therapy HIV-Associated Lipodystrophy Syndrome - metabolism Homeostasis Human immunodeficiency virus Human viral diseases Humans Infectious diseases Lymphocyte Activation - physiology Male Medical sciences Microbiology Middle Aged Miscellaneous Patients Phosphorylation Risk factors STAT5 Transcription Factor - genetics STAT5 Transcription Factor - metabolism T cell receptors Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Load Viremia Virology
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