Modulation of the Bacillus anthracis Secretome by the Immune Inhibitor A1 Protease

The Bacillus anthracis secretome includes protective antigen, lethal factor, and edema factor, which are the components of anthrax toxin, and other proteins with known or potential roles in anthrax disease. Immune inhibitor A1 (InhA1) is a secreted metalloprotease that is unique to pathogenic member...

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Veröffentlicht in:	Journal of Bacteriology 2014-01, Vol.196 (2), p.424-435
Hauptverfasser:	Pflughoeft, Kathryn J, Swick, Michelle C, Engler, David A, Yeo, Hye-Jeong, Koehler, Theresa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Anthrax anthrax toxin Antigens, Bacterial - metabolism Bacillus anthracis Bacillus anthracis - genetics Bacillus anthracis - metabolism Bacterial Proteins - metabolism Bacterial Toxins - metabolism Bacteriology Binding Sites edema Electrophoresis Gene Deletion mammals Metalloendopeptidases - genetics Metalloendopeptidases - metabolism metalloproteinases mutants Mutation Probiotics Proteases Protein Binding Proteins proteolysis Proteome - analysis virulence zinc Zinc - metabolism
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