Preimplantation genetic diagnosis for X;autosome translocations: lessons from a case of misdiagnosis

Preimplantation genetic diagnosis (PGD) is offered to couples carrying a reciprocal translocation in an attempt to increase their chance of phenotypically normal offspring. For the selection of embryos that are balanced for the translocation chromosomes, it is critical to use a combination of DNA pr...

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Veröffentlicht in:	Human reproduction (Oxford) 2013-11, Vol.28 (11), p.3141-3145
Hauptverfasser:	Van Echten-Arends, J., Coonen, E., Reuters, B., Suijkerbuijk, R.F., Dul, E.C., Land, J.A., van Ravenswaaij-Arts, C.M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Spontaneous Adult Blastomeres Chromosome Disorders - diagnosis Chromosomes, Human, X Diagnostic Errors Female Humans Male Pregnancy Preimplantation Diagnosis - methods Translocation, Genetic
Online-Zugang:	Volltext
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