Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China
Abstract Purpose Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD. Methods A total of 1...
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Veröffentlicht in: | Comprehensive psychiatry 2013-11, Vol.54 (8), p.1198-1202 |
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creator | Xiang, Yu-Tao Wang, Gang Guo, Tong Hu, Chen Ungvari, Gabor S Kilbourne, Amy M Lai, Kelly Y.C Wong, Samuel Y.S Si, Tian-Mei Zheng, Qi-Wen Chen, Da-Fang Fang, Yi-Ru Lu, Zheng Yang, Hai-Chen Hu, Jian Chen, Zhi-Yu Huang, Yi Sun, Jing Wang, Xiao-Ping Li, Hui-Chun Zhang, Jin-Bei Chiu, Helen F.K |
description | Abstract Purpose Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD. Methods A total of 1178 patients with MDD from 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide were enrolled. Cross-sectional data including patients' demographic and clinical characteristics and prescriptions of psychotropic medications were recorded using a standardized protocol and data collection procedure. Results The sample consisted of 793 female and 385 male patients. Univariate analyses revealed that male patients were younger than female patients, had a younger age of onset of depression, had less lifetime depressive episodes and had more bipolar features (i.e. patients who screened positive for hypomanic symptoms on the 32-item Hypomania Checklist, but did not meet the diagnostic criteria for DSM-IV bipolar disorders as measured by the Mini International Neuropsychiatric Interview). Also, men were more likely to be employed than women and less likely to have depressive episodes following stressful life events. In multivariate analyses, being employed, having bipolar features and not having depressive episodes following stressful life events were independently associated with being a male patient with major depressive disorder. There was no difference in use of psychotropic medications by gender. Conclusions Most gender differences in MDD patients in this study are not consistent with findings of Western studies suggesting that gender differences in MDD may be determined by both biological and sociocultural differences among ethnically different patient populations. |
doi_str_mv | 10.1016/j.comppsych.2013.04.018 |
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fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1492617113</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S0010440X13001375</els_id><sourcerecordid>1448208499</sourcerecordid><originalsourceid>FETCH-LOGICAL-c517t-506b4a8aa5acaaf4041501a5c89eb4b2febbce38b9d3e700d918824f4b1216673</originalsourceid><addsrcrecordid>eNqNksFu1DAQhi0EosvCK4AlhMQlYRw7iXNBqlZQkCpxACRuluNMug4bO9jZon0bHhWnu22lnnqyZX3z-5_5h5A3DHIGrPow5MaP0xQPZpsXwHgOIgcmn5AVK3mRSS7FU7ICYJAJAb_OyIsYBwCQUorn5Kzgsqy4bFbk3wW6DgPtbN9jQGcwUutoh6O_CnraWkO166jZWWeN3tEe9bwPCVpep3QxwbbWXdFJzzMGF6nv6Y0vPwc_pfIRu1Q5W-9ulBNn0c2R_rXzlo568OlzXJSivcbkI_qwGEroZmudfkme9XoX8dXpXJOfnz_92HzJLr9dfN2cX2amZPWclVC1QkutS2207gUIVgLTpZENtqItemxbg1y2TcexBugaJmUhetGyglVVzdfk_VF3Cv7PHuOsRhsN7nbaod9HxURTVKxmjD8CFbIAKZomoW8foIPfB5caWahKCF6LMlH1kTLBxxiwV1Owow4HxUAteatB3eWtlrwVCJXyTpWvT_r7Ng36ru424AS8OwE6pvz6oJ2x8Z6rG6ghoWtyfuQwzfjaYlDR2GUdOhvQzKrz9hFmPj7QuF2b33jAeN-5ioUC9X1Zz2U7GU83Xpf8P8W05Zg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1446443745</pqid></control><display><type>article</type><title>Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><source>ProQuest Central UK/Ireland</source><creator>Xiang, Yu-Tao ; Wang, Gang ; Guo, Tong ; Hu, Chen ; Ungvari, Gabor S ; Kilbourne, Amy M ; Lai, Kelly Y.C ; Wong, Samuel Y.S ; Si, Tian-Mei ; Zheng, Qi-Wen ; Chen, Da-Fang ; Fang, Yi-Ru ; Lu, Zheng ; Yang, Hai-Chen ; Hu, Jian ; Chen, Zhi-Yu ; Huang, Yi ; Sun, Jing ; Wang, Xiao-Ping ; Li, Hui-Chun ; Zhang, Jin-Bei ; Chiu, Helen F.K</creator><creatorcontrib>Xiang, Yu-Tao ; Wang, Gang ; Guo, Tong ; Hu, Chen ; Ungvari, Gabor S ; Kilbourne, Amy M ; Lai, Kelly Y.C ; Wong, Samuel Y.S ; Si, Tian-Mei ; Zheng, Qi-Wen ; Chen, Da-Fang ; Fang, Yi-Ru ; Lu, Zheng ; Yang, Hai-Chen ; Hu, Jian ; Chen, Zhi-Yu ; Huang, Yi ; Sun, Jing ; Wang, Xiao-Ping ; Li, Hui-Chun ; Zhang, Jin-Bei ; Chiu, Helen F.K</creatorcontrib><description>Abstract Purpose Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD. Methods A total of 1178 patients with MDD from 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide were enrolled. Cross-sectional data including patients' demographic and clinical characteristics and prescriptions of psychotropic medications were recorded using a standardized protocol and data collection procedure. Results The sample consisted of 793 female and 385 male patients. Univariate analyses revealed that male patients were younger than female patients, had a younger age of onset of depression, had less lifetime depressive episodes and had more bipolar features (i.e. patients who screened positive for hypomanic symptoms on the 32-item Hypomania Checklist, but did not meet the diagnostic criteria for DSM-IV bipolar disorders as measured by the Mini International Neuropsychiatric Interview). Also, men were more likely to be employed than women and less likely to have depressive episodes following stressful life events. In multivariate analyses, being employed, having bipolar features and not having depressive episodes following stressful life events were independently associated with being a male patient with major depressive disorder. There was no difference in use of psychotropic medications by gender. Conclusions Most gender differences in MDD patients in this study are not consistent with findings of Western studies suggesting that gender differences in MDD may be determined by both biological and sociocultural differences among ethnically different patient populations.</description><identifier>ISSN: 0010-440X</identifier><identifier>EISSN: 1532-8384</identifier><identifier>DOI: 10.1016/j.comppsych.2013.04.018</identifier><identifier>PMID: 23856389</identifier><identifier>CODEN: COPYAV</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Adult and adolescent clinical studies ; Age ; Age Factors ; Age of Onset ; Biological and medical sciences ; Bipolar Disorder - epidemiology ; Bipolar Disorder - physiopathology ; China - epidemiology ; Comorbidity ; Cross-Cultural Comparison ; Cross-Sectional Studies ; Depression ; Depressive Disorder, Major - epidemiology ; Depressive Disorder, Major - physiopathology ; Drug Prescriptions - statistics & numerical data ; Electroconvulsive therapy ; Employment - statistics & numerical data ; Female ; Gender differences ; Humans ; Life Change Events ; Male ; Medical sciences ; Mental depression ; Middle Aged ; Miscellaneous ; Mood disorders ; Practice Patterns, Physicians' - statistics & numerical data ; Psychiatry ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Psychotropic Drugs - therapeutic use ; Sex Factors ; Studies</subject><ispartof>Comprehensive psychiatry, 2013-11, Vol.54 (8), p.1198-1202</ispartof><rights>Elsevier Inc.</rights><rights>2013 Elsevier Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2013 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Jan 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-506b4a8aa5acaaf4041501a5c89eb4b2febbce38b9d3e700d918824f4b1216673</citedby><cites>FETCH-LOGICAL-c517t-506b4a8aa5acaaf4041501a5c89eb4b2febbce38b9d3e700d918824f4b1216673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1446443745?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=27907056$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23856389$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Xiang, Yu-Tao</creatorcontrib><creatorcontrib>Wang, Gang</creatorcontrib><creatorcontrib>Guo, Tong</creatorcontrib><creatorcontrib>Hu, Chen</creatorcontrib><creatorcontrib>Ungvari, Gabor S</creatorcontrib><creatorcontrib>Kilbourne, Amy M</creatorcontrib><creatorcontrib>Lai, Kelly Y.C</creatorcontrib><creatorcontrib>Wong, Samuel Y.S</creatorcontrib><creatorcontrib>Si, Tian-Mei</creatorcontrib><creatorcontrib>Zheng, Qi-Wen</creatorcontrib><creatorcontrib>Chen, Da-Fang</creatorcontrib><creatorcontrib>Fang, Yi-Ru</creatorcontrib><creatorcontrib>Lu, Zheng</creatorcontrib><creatorcontrib>Yang, Hai-Chen</creatorcontrib><creatorcontrib>Hu, Jian</creatorcontrib><creatorcontrib>Chen, Zhi-Yu</creatorcontrib><creatorcontrib>Huang, Yi</creatorcontrib><creatorcontrib>Sun, Jing</creatorcontrib><creatorcontrib>Wang, Xiao-Ping</creatorcontrib><creatorcontrib>Li, Hui-Chun</creatorcontrib><creatorcontrib>Zhang, Jin-Bei</creatorcontrib><creatorcontrib>Chiu, Helen F.K</creatorcontrib><title>Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China</title><title>Comprehensive psychiatry</title><addtitle>Compr Psychiatry</addtitle><description>Abstract Purpose Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD. Methods A total of 1178 patients with MDD from 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide were enrolled. Cross-sectional data including patients' demographic and clinical characteristics and prescriptions of psychotropic medications were recorded using a standardized protocol and data collection procedure. Results The sample consisted of 793 female and 385 male patients. Univariate analyses revealed that male patients were younger than female patients, had a younger age of onset of depression, had less lifetime depressive episodes and had more bipolar features (i.e. patients who screened positive for hypomanic symptoms on the 32-item Hypomania Checklist, but did not meet the diagnostic criteria for DSM-IV bipolar disorders as measured by the Mini International Neuropsychiatric Interview). Also, men were more likely to be employed than women and less likely to have depressive episodes following stressful life events. In multivariate analyses, being employed, having bipolar features and not having depressive episodes following stressful life events were independently associated with being a male patient with major depressive disorder. There was no difference in use of psychotropic medications by gender. Conclusions Most gender differences in MDD patients in this study are not consistent with findings of Western studies suggesting that gender differences in MDD may be determined by both biological and sociocultural differences among ethnically different patient populations.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Age</subject><subject>Age Factors</subject><subject>Age of Onset</subject><subject>Biological and medical sciences</subject><subject>Bipolar Disorder - epidemiology</subject><subject>Bipolar Disorder - physiopathology</subject><subject>China - epidemiology</subject><subject>Comorbidity</subject><subject>Cross-Cultural Comparison</subject><subject>Cross-Sectional Studies</subject><subject>Depression</subject><subject>Depressive Disorder, Major - epidemiology</subject><subject>Depressive Disorder, Major - physiopathology</subject><subject>Drug Prescriptions - statistics & numerical data</subject><subject>Electroconvulsive therapy</subject><subject>Employment - statistics & numerical data</subject><subject>Female</subject><subject>Gender differences</subject><subject>Humans</subject><subject>Life Change Events</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mood disorders</subject><subject>Practice Patterns, Physicians' - statistics & numerical data</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Psychotropic Drugs - therapeutic use</subject><subject>Sex Factors</subject><subject>Studies</subject><issn>0010-440X</issn><issn>1532-8384</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNksFu1DAQhi0EosvCK4AlhMQlYRw7iXNBqlZQkCpxACRuluNMug4bO9jZon0bHhWnu22lnnqyZX3z-5_5h5A3DHIGrPow5MaP0xQPZpsXwHgOIgcmn5AVK3mRSS7FU7ICYJAJAb_OyIsYBwCQUorn5Kzgsqy4bFbk3wW6DgPtbN9jQGcwUutoh6O_CnraWkO166jZWWeN3tEe9bwPCVpep3QxwbbWXdFJzzMGF6nv6Y0vPwc_pfIRu1Q5W-9ulBNn0c2R_rXzlo568OlzXJSivcbkI_qwGEroZmudfkme9XoX8dXpXJOfnz_92HzJLr9dfN2cX2amZPWclVC1QkutS2207gUIVgLTpZENtqItemxbg1y2TcexBugaJmUhetGyglVVzdfk_VF3Cv7PHuOsRhsN7nbaod9HxURTVKxmjD8CFbIAKZomoW8foIPfB5caWahKCF6LMlH1kTLBxxiwV1Owow4HxUAteatB3eWtlrwVCJXyTpWvT_r7Ng36ru424AS8OwE6pvz6oJ2x8Z6rG6ghoWtyfuQwzfjaYlDR2GUdOhvQzKrz9hFmPj7QuF2b33jAeN-5ioUC9X1Zz2U7GU83Xpf8P8W05Zg</recordid><startdate>20131101</startdate><enddate>20131101</enddate><creator>Xiang, Yu-Tao</creator><creator>Wang, Gang</creator><creator>Guo, Tong</creator><creator>Hu, Chen</creator><creator>Ungvari, Gabor S</creator><creator>Kilbourne, Amy M</creator><creator>Lai, Kelly Y.C</creator><creator>Wong, Samuel Y.S</creator><creator>Si, Tian-Mei</creator><creator>Zheng, Qi-Wen</creator><creator>Chen, Da-Fang</creator><creator>Fang, Yi-Ru</creator><creator>Lu, Zheng</creator><creator>Yang, Hai-Chen</creator><creator>Hu, Jian</creator><creator>Chen, Zhi-Yu</creator><creator>Huang, Yi</creator><creator>Sun, Jing</creator><creator>Wang, Xiao-Ping</creator><creator>Li, Hui-Chun</creator><creator>Zhang, Jin-Bei</creator><creator>Chiu, Helen F.K</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20131101</creationdate><title>Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China</title><author>Xiang, Yu-Tao ; Wang, Gang ; Guo, Tong ; Hu, Chen ; Ungvari, Gabor S ; Kilbourne, Amy M ; Lai, Kelly Y.C ; Wong, Samuel Y.S ; Si, Tian-Mei ; Zheng, Qi-Wen ; Chen, Da-Fang ; Fang, Yi-Ru ; Lu, Zheng ; Yang, Hai-Chen ; Hu, Jian ; Chen, Zhi-Yu ; Huang, Yi ; Sun, Jing ; Wang, Xiao-Ping ; Li, Hui-Chun ; Zhang, Jin-Bei ; Chiu, Helen F.K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-506b4a8aa5acaaf4041501a5c89eb4b2febbce38b9d3e700d918824f4b1216673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Age</topic><topic>Age Factors</topic><topic>Age of Onset</topic><topic>Biological and medical sciences</topic><topic>Bipolar Disorder - epidemiology</topic><topic>Bipolar Disorder - physiopathology</topic><topic>China - epidemiology</topic><topic>Comorbidity</topic><topic>Cross-Cultural Comparison</topic><topic>Cross-Sectional Studies</topic><topic>Depression</topic><topic>Depressive Disorder, Major - epidemiology</topic><topic>Depressive Disorder, Major - physiopathology</topic><topic>Drug Prescriptions - statistics & numerical data</topic><topic>Electroconvulsive therapy</topic><topic>Employment - statistics & numerical data</topic><topic>Female</topic><topic>Gender differences</topic><topic>Humans</topic><topic>Life Change Events</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mood disorders</topic><topic>Practice Patterns, Physicians' - statistics & numerical data</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Psychotropic Drugs - therapeutic use</topic><topic>Sex Factors</topic><topic>Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Xiang, Yu-Tao</creatorcontrib><creatorcontrib>Wang, Gang</creatorcontrib><creatorcontrib>Guo, Tong</creatorcontrib><creatorcontrib>Hu, Chen</creatorcontrib><creatorcontrib>Ungvari, Gabor S</creatorcontrib><creatorcontrib>Kilbourne, Amy M</creatorcontrib><creatorcontrib>Lai, Kelly Y.C</creatorcontrib><creatorcontrib>Wong, Samuel Y.S</creatorcontrib><creatorcontrib>Si, Tian-Mei</creatorcontrib><creatorcontrib>Zheng, Qi-Wen</creatorcontrib><creatorcontrib>Chen, Da-Fang</creatorcontrib><creatorcontrib>Fang, Yi-Ru</creatorcontrib><creatorcontrib>Lu, Zheng</creatorcontrib><creatorcontrib>Yang, Hai-Chen</creatorcontrib><creatorcontrib>Hu, Jian</creatorcontrib><creatorcontrib>Chen, Zhi-Yu</creatorcontrib><creatorcontrib>Huang, Yi</creatorcontrib><creatorcontrib>Sun, Jing</creatorcontrib><creatorcontrib>Wang, Xiao-Ping</creatorcontrib><creatorcontrib>Li, Hui-Chun</creatorcontrib><creatorcontrib>Zhang, Jin-Bei</creatorcontrib><creatorcontrib>Chiu, Helen F.K</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Comprehensive psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Xiang, Yu-Tao</au><au>Wang, Gang</au><au>Guo, Tong</au><au>Hu, Chen</au><au>Ungvari, Gabor S</au><au>Kilbourne, Amy M</au><au>Lai, Kelly Y.C</au><au>Wong, Samuel Y.S</au><au>Si, Tian-Mei</au><au>Zheng, Qi-Wen</au><au>Chen, Da-Fang</au><au>Fang, Yi-Ru</au><au>Lu, Zheng</au><au>Yang, Hai-Chen</au><au>Hu, Jian</au><au>Chen, Zhi-Yu</au><au>Huang, Yi</au><au>Sun, Jing</au><au>Wang, Xiao-Ping</au><au>Li, Hui-Chun</au><au>Zhang, Jin-Bei</au><au>Chiu, Helen F.K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China</atitle><jtitle>Comprehensive psychiatry</jtitle><addtitle>Compr Psychiatry</addtitle><date>2013-11-01</date><risdate>2013</risdate><volume>54</volume><issue>8</issue><spage>1198</spage><epage>1202</epage><pages>1198-1202</pages><issn>0010-440X</issn><eissn>1532-8384</eissn><coden>COPYAV</coden><abstract>Abstract Purpose Little is known about gender differences associated with major depressive disorder (MDD) in China. This study examined gender differences associated with other demographic and clinical characteristics and psychotropic drug treatment in Chinese patients with MDD. Methods A total of 1178 patients with MDD from 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide were enrolled. Cross-sectional data including patients' demographic and clinical characteristics and prescriptions of psychotropic medications were recorded using a standardized protocol and data collection procedure. Results The sample consisted of 793 female and 385 male patients. Univariate analyses revealed that male patients were younger than female patients, had a younger age of onset of depression, had less lifetime depressive episodes and had more bipolar features (i.e. patients who screened positive for hypomanic symptoms on the 32-item Hypomania Checklist, but did not meet the diagnostic criteria for DSM-IV bipolar disorders as measured by the Mini International Neuropsychiatric Interview). Also, men were more likely to be employed than women and less likely to have depressive episodes following stressful life events. In multivariate analyses, being employed, having bipolar features and not having depressive episodes following stressful life events were independently associated with being a male patient with major depressive disorder. There was no difference in use of psychotropic medications by gender. Conclusions Most gender differences in MDD patients in this study are not consistent with findings of Western studies suggesting that gender differences in MDD may be determined by both biological and sociocultural differences among ethnically different patient populations.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>23856389</pmid><doi>10.1016/j.comppsych.2013.04.018</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Adult and adolescent clinical studies Age Age Factors Age of Onset Biological and medical sciences Bipolar Disorder - epidemiology Bipolar Disorder - physiopathology China - epidemiology Comorbidity Cross-Cultural Comparison Cross-Sectional Studies Depression Depressive Disorder, Major - epidemiology Depressive Disorder, Major - physiopathology Drug Prescriptions - statistics & numerical data Electroconvulsive therapy Employment - statistics & numerical data Female Gender differences Humans Life Change Events Male Medical sciences Mental depression Middle Aged Miscellaneous Mood disorders Practice Patterns, Physicians' - statistics & numerical data Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychotropic Drugs - therapeutic use Sex Factors Studies |
title | Gender differences in demographic and clinical features and prescribing patterns of psychotropic medications in patients with major depressive disorder in China |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T03%3A00%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Gender%20differences%20in%20demographic%20and%20clinical%20features%20and%20prescribing%20patterns%20of%20psychotropic%20medications%20in%20patients%20with%20major%20depressive%20disorder%20in%20China&rft.jtitle=Comprehensive%20psychiatry&rft.au=Xiang,%20Yu-Tao&rft.date=2013-11-01&rft.volume=54&rft.issue=8&rft.spage=1198&rft.epage=1202&rft.pages=1198-1202&rft.issn=0010-440X&rft.eissn=1532-8384&rft.coden=COPYAV&rft_id=info:doi/10.1016/j.comppsych.2013.04.018&rft_dat=%3Cproquest_cross%3E1448208499%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1446443745&rft_id=info:pmid/23856389&rft_els_id=1_s2_0_S0010440X13001375&rfr_iscdi=true |