Anorectal neural crest derived cell behavior after the migration of vagal neural crest derived cells is surgically disrupted: implications for the etiology of Hirschsprung’s disease
Background/purpose In Hirschsprung’s disease (HD), thick extrinsic nerve fibers can be associated with the aganglionic segment in the anorectum. We surgically disrupted the migration of vagal neural crest cell-derived cells (vagal NCC) in embryos from transgenic mice we created previously (SOX10-VEN...
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Veröffentlicht in: | Pediatric surgery international 2013-01, Vol.29 (1), p.9-12 |
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