Effects of amphotericin B on Aspergillus flavus clinical isolates with variable susceptibilities to the polyene in an experimental model of systemic aspergillosis

The aim of the present study was to evaluate the effects of amphotericin B (AMB) on clinical isolates of Aspergillus flavus. MICs of both standard AMB and liposomal AMB (L-AMB) were determined using a broth dilution method for seven isolates of A. flavus. AMB MICs were also determined using the Etes...

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2013-11, Vol.68 (11), p.2587-2591
Hauptverfasser:	Barchiesi, Francesco, Spreghini, Elisabetta, Sanguinetti, Maurizio, Giannini, Daniele, Manso, Esther, Castelli, Pamela, Girmenia, Corrado
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Amphotericin B - therapeutic use Animals Antibiotics Antifungal Agents - therapeutic use Antimicrobial agents Aspergillosis - microbiology Aspergillus flavus Aspergillus flavus - drug effects Aspergillus flavus - isolation & purification Disease Models, Animal Drug resistance Drug Resistance, Fungal Female Fungal infections Fungi Mice Microbial Sensitivity Tests Polyenes - therapeutic use Survival Analysis Treatment Outcome
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