A review of the potential protective effects of pentoxifylline against drug-induced nephrotoxicity

Purpose Drug-induced nephrotoxicity is one of the most common side effects of medications and accounts for about 20 % of hospital admissions for acute kidney injury (AKI). Some possible pharmacologic mechanisms of pentoxifylline (PTX) that suggest it as a candidate to ameliorate AKI include interact...

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Veröffentlicht in:	European journal of clinical pharmacology 2013-05, Vol.69 (5), p.1057-1073
Hauptverfasser:	Nasiri-Toosi, Zahra, Dashti-Khavidaki, Simin, Khalili, Hossein, Lessan-Pezeshki, Mahboob
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - chemically induced Acute Kidney Injury - prevention & control Adenosine receptors Animals Anti-Infective Agents - adverse effects Biological and medical sciences Biomedical and Life Sciences Biomedicine Contrast Media - adverse effects Cytotoxins - adverse effects Drug therapy Humans Immunosuppressive Agents - adverse effects Kidney - drug effects Medical sciences Nephrology Pentoxifylline - pharmacology Pentoxifylline - therapeutic use Pharmacology. Drug treatments Pharmacology/Toxicology Review Article Toxicity Vasodilator Agents - pharmacology Vasodilator Agents - therapeutic use
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