Regulation of antibacterial (antitubercular) immunity mediated by T-helper type-17 lymphocytes
An analysis of the current views on the functional and immunoregulatory role of T-helper type-17 lymphocytes (Thl7) in the anti-infectious immune response, in particular in the development of the protective immune reactions to intracellular pathogens is presented. Special attention is paid to the pa...
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| Veröffentlicht in: | Molecular biology (New York) 2013-11, Vol.47 (6), p.769-775 |
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| container_title | Molecular biology (New York) |
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| creator | Kononova, T. E. Urazova, O. I. Novitskii, V. V. Churina, E. G. |
| description | An analysis of the current views on the functional and immunoregulatory role of T-helper type-17 lymphocytes (Thl7) in the anti-infectious immune response, in particular in the development of the protective immune reactions to intracellular pathogens is presented. Special attention is paid to the participation of these lymphocytes and the cytokines produced by them in immune response to the invasion of
Mycobacterium tuberculosis
. The molecular mechanisms, underlying the predominant development of Th17 lymphocytes and/or regulatory T cells (Treg) with the evaluation of the interconnection of these cell subpopulations in the formation of an immune imbalance in infectious pathology are studied. |
| doi_str_mv | 10.1134/S0026893313050087 |
| format | Article |
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Mycobacterium tuberculosis
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Mycobacterium tuberculosis
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| subjects | Biochemistry Biomedical and Life Sciences Cytokines Human Genetics Immunology Life Sciences Lymphocytes Molecular biology Mycobacterium tuberculosis Pathology Reviews Tuberculosis |
| title | Regulation of antibacterial (antitubercular) immunity mediated by T-helper type-17 lymphocytes |
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