Hypolipidemic and Toxicological Potential of Aqueous Extract of Rauvolfia vomitoria Afzel Root in Wistar Rats

The aim of this study was to investigate the hypolipidemic potential of aqueous extract of Rauvolfia vomitoria root and assess its toxicological effect in selected tissues of rats. Aqueous extract of Rauvolfia vomitoria root was administered to wistar rats daily at 24 h interval at a dosage of 200 m...

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Veröffentlicht in:Journal of medical sciences (Faisalābād, Pakistan) Pakistan), 2013, Vol.13 (4), p.253-260
Hauptverfasser: Akanji, M.A., Yakubu, M.T., Kazeem, M.I.
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Sprache:eng
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Zusammenfassung:The aim of this study was to investigate the hypolipidemic potential of aqueous extract of Rauvolfia vomitoria root and assess its toxicological effect in selected tissues of rats. Aqueous extract of Rauvolfia vomitoria root was administered to wistar rats daily at 24 h interval at a dosage of 200 mg kg super( -1) b.wt. following which the rats were sacrificed after receiving 1, 3, 5, 10, 20 and 30 daily oral doses. Administration of the extract produced significant reduction (p
ISSN:1682-4474
1812-5727
DOI:10.3923/jms.2013.253.260