CXCL12, CXCR4 and IFNγ genes expression: implications for proinflammatory microenvironment of breast cancer

Signals from the microenvironment have a profound influence on the maintenance or progression of breast cancer. In the present study, the frequency of CXCL12 rs1801157 polymorphism in peripheral blood and the expression of CXCL12, CXCR4 and IFNγ mRNA in normal and mammary gland tumor tissues were as...

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Veröffentlicht in:	Clinical and experimental medicine 2013-08, Vol.13 (3), p.211-219
Hauptverfasser:	de Oliveira, Karen Brajão, Guembarovski, Roberta Losi, Guembarovski, Alda Maria Fiorina Losi, da Silva do Amaral Herrera, Ana Cristina, Sobrinho, Walter Jorge, Ariza, Carolina Batista, Watanabe, Maria Angelica Ehara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Breast cancer Breast Neoplasms - immunology Breast Neoplasms - pathology Chemokine CXCL12 - biosynthesis Chemokine CXCL12 - genetics Female Gene Expression Genotype Hematology Humans Interferon-gamma - biosynthesis Interferon-gamma - genetics Internal Medicine Medicine Medicine & Public Health Middle Aged Oncology Original Article Polymerase Chain Reaction Polymorphism, Single Nucleotide Receptors, CXCR4 - biosynthesis Receptors, CXCR4 - genetics RNA, Messenger - biosynthesis RNA, Messenger - genetics
Online-Zugang:	Volltext
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