Heat-shock proteins in stromal joint tissues: innocent bystanders or disease-initiating proteins?

Heat-shock proteins (HSPs) are molecular chaperones that are highly conserved between species. In recent decades it has become clear that these proteins play an important role in the pathogenesis of inflammatory and degenerative joint diseases by (dys)regulating the immune system and by direct effec...

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2014-02, Vol.53 (2), p.223-232
Hauptverfasser:	Lambrecht, Stijn, Juchtmans, Nele, Elewaut, Dirk
Format:	Artikel
Sprache:	eng
Schlagworte:	Connective Tissue - physiopathology Heat-Shock Proteins - physiology Homeostasis - physiology Humans Immune System - physiopathology Joint Diseases - physiopathology Molecular Chaperones - physiology
Online-Zugang:	Volltext
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