Efficacy of an Interferon- and Ribavirin-Free Regimen of Daclatasvir, Asunaprevir, and BMS-791325 in Treatment-Naive Patients With HCV Genotype 1 Infection

Background & Aims The combination of peginterferon and ribavirin with telaprevir or boceprevir is the standard treatment of hepatitis C virus (HCV) genotype 1 infection. However, these drugs are not well tolerated because of their side effects and suboptimal virologic responses. In a phase 2a, o...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2014-02, Vol.146 (2), p.420-429
Hauptverfasser:	Everson, Gregory T, Sims, Karen D, Rodriguez-Torres, Maribel, Hézode, Christophe, Lawitz, Eric, Bourlière, Marc, Loustaud-Ratti, Veronique, Rustgi, Vinod, Schwartz, Howard, Tatum, Harvey, Marcellin, Patrick, Pol, Stanislas, Thuluvath, Paul J, Eley, Timothy, Wang, Xiaodong, Huang, Shu-Pang, McPhee, Fiona, Wind-Rotolo, Megan, Chung, Ellen, Pasquinelli, Claudio, Grasela, Dennis M, Gardiner, David F
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Aged Antiviral Agents - therapeutic use Benzazepines - therapeutic use DAA Drug Administration Schedule Drug Combination Drug Therapy, Combination Female Gastroenterology and Hepatology Genotype Hepacivirus - genetics Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology Humans Imidazoles - therapeutic use Indoles - therapeutic use Intention to Treat Analysis Isoquinolines - therapeutic use Liver Disease Male Middle Aged Pilot Projects Sulfonamides - therapeutic use Therapy Treatment Outcome Viral Load Young Adult
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