Synthesis and antimicrobial activity of α-aminoboronic-containing peptidomimetics

A library of 175 dipeptidomimetics and tripeptidomimetics containing an α‐amino boronic acid or boronate has been synthesized, and the activity toward Mycobacterium tuberculosis, Candida albicans, Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli and Pseudomonas aeruginosa has been scr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of peptide science 2014-01, Vol.20 (1), p.20-24
Hauptverfasser:	Gozhina, Olga V., Svendsen, John Sigurd, Lejon, Tore
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - pharmacology Antifungal Agents - chemical synthesis Antifungal Agents - pharmacology antimicrobials Boronic Acids - chemical synthesis Boronic Acids - pharmacology Candida albicans - drug effects Escherichia coli - drug effects Hep G2 Cells Humans Matteson homologation Microbial Sensitivity Tests Molecular Mimicry Mycobacterium tuberculosis - drug effects Peptidomimetics - chemical synthesis Peptidomimetics - pharmacology Pseudomonas aeruginosa - drug effects Staphylococcus aureus - drug effects Streptococcus pyogenes - drug effects Structure-Activity Relationship α-amino boronate α-amino boronic acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!