Difficulties in reaching therapeutic goals for hypertension and dysplipidaemia in patients with type 2 diabetes in general practice
National guidelines recommend strict control of blood pressure (BP) and plasma low-density lipoprotein cholesterol (LDL) in type 2 diabetes (T2DM), aiming at a BP ≤ 130/80 mmHg and an LDL concentration ≤ 2.5 mmol/l. Angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II-receptor blockers...
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| Veröffentlicht in: | Danish medical journal 2013-12, Vol.60 (12), p.A4740-A4740 |
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| creator | Knudsen, Søren Tang Mosbech, Thomas Hammershaimb Hansen, Birtha Kønig, Else Johnsen, Peter Christian Kamper, Anne-Lise |
| description | National guidelines recommend strict control of blood pressure (BP) and plasma low-density lipoprotein cholesterol (LDL) in type 2 diabetes (T2DM), aiming at a BP ≤ 130/80 mmHg and an LDL concentration ≤ 2.5 mmol/l. Angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II-receptor blockers (ARB) are recommended as primary antihypertensive therapy (AHT). To which extent these targets are met in Danish primary care is unknown.
This study was based on data from 2,057 patients with T2DM who were randomly selected from 64 general practitioners (GPs) from different regions of Denmark. Data were collected from the GPs' electronic records.
The mean age ± standard deviation was 66.2 ± 11.6 years; 58.7% were male. The mean systolic BP ± standard deviation was 132.6 ± 14.6 mmHg and the mean diastolic BP ± standard deviation was 78.1 ± 9.0 mmHg. 47.7% of the patients met the BP target. 79.5% of the patients were on AHT. 55.1% of the untreated and 46.0% of the treated patients met the BP target. 83.4% of the treated patients received ACEI or ARB. The median LDL was 2.2 (1.7-2.7) mmol/l. 63.7% of the patients met the LDL target. 73.7% of the patients received lipid-lowering therapy. 32.8% of the untreated and 74.4% of the treated patients met the LDL target.
AHT including ACEI and ARB and lipid-lowering therapy are widely used in T2DM in Danish primary care, but only half of the patients are at target for BP and two thirds are at target for LDL. Increased use of diuretics may improve BP control.
This study was funded by a grant from Boehringer Ingelheim, Denmark. The grant covered costs related to data collection, time spent by the general practitioners and data analysis by the DTU.
not relevant. |
| format | Article |
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This study was based on data from 2,057 patients with T2DM who were randomly selected from 64 general practitioners (GPs) from different regions of Denmark. Data were collected from the GPs' electronic records.
The mean age ± standard deviation was 66.2 ± 11.6 years; 58.7% were male. The mean systolic BP ± standard deviation was 132.6 ± 14.6 mmHg and the mean diastolic BP ± standard deviation was 78.1 ± 9.0 mmHg. 47.7% of the patients met the BP target. 79.5% of the patients were on AHT. 55.1% of the untreated and 46.0% of the treated patients met the BP target. 83.4% of the treated patients received ACEI or ARB. The median LDL was 2.2 (1.7-2.7) mmol/l. 63.7% of the patients met the LDL target. 73.7% of the patients received lipid-lowering therapy. 32.8% of the untreated and 74.4% of the treated patients met the LDL target.
AHT including ACEI and ARB and lipid-lowering therapy are widely used in T2DM in Danish primary care, but only half of the patients are at target for BP and two thirds are at target for LDL. Increased use of diuretics may improve BP control.
This study was funded by a grant from Boehringer Ingelheim, Denmark. The grant covered costs related to data collection, time spent by the general practitioners and data analysis by the DTU.
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This study was based on data from 2,057 patients with T2DM who were randomly selected from 64 general practitioners (GPs) from different regions of Denmark. Data were collected from the GPs' electronic records.
The mean age ± standard deviation was 66.2 ± 11.6 years; 58.7% were male. The mean systolic BP ± standard deviation was 132.6 ± 14.6 mmHg and the mean diastolic BP ± standard deviation was 78.1 ± 9.0 mmHg. 47.7% of the patients met the BP target. 79.5% of the patients were on AHT. 55.1% of the untreated and 46.0% of the treated patients met the BP target. 83.4% of the treated patients received ACEI or ARB. The median LDL was 2.2 (1.7-2.7) mmol/l. 63.7% of the patients met the LDL target. 73.7% of the patients received lipid-lowering therapy. 32.8% of the untreated and 74.4% of the treated patients met the LDL target.
AHT including ACEI and ARB and lipid-lowering therapy are widely used in T2DM in Danish primary care, but only half of the patients are at target for BP and two thirds are at target for LDL. Increased use of diuretics may improve BP control.
This study was funded by a grant from Boehringer Ingelheim, Denmark. The grant covered costs related to data collection, time spent by the general practitioners and data analysis by the DTU.
not relevant.</description><subject>Aged</subject><subject>Angiotensin Receptor Antagonists - therapeutic use</subject><subject>Angiotensin-Converting Enzyme Inhibitors - therapeutic use</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Blood Pressure</subject><subject>Cholesterol, LDL - blood</subject><subject>Denmark</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - drug therapy</subject><subject>Female</subject><subject>General Practice</subject><subject>Humans</subject><subject>Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use</subject><subject>Hypercholesterolemia - blood</subject><subject>Hypercholesterolemia - complications</subject><subject>Hypercholesterolemia - drug therapy</subject><subject>Hypertension - complications</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - physiopathology</subject><subject>Hypoglycemic Agents - therapeutic use</subject><subject>Hypolipidemic Agents - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patient Care Planning</subject><subject>Practice Guidelines as Topic</subject><subject>Treatment Outcome</subject><issn>2245-1919</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo10E1LxDAQBuAiiLvo_gXJ0Uuh-WizOcr6CQte9Fym6WQbadOYpMie_eNGdp3LXN55ZpiLYs2YqEuqqFoVmxg_q1wNa7a0uipWTPC6FkKti58Ha4zVy5gsRmIdCQh6sO5A0oABPC7JanKYYYzEzIEMR48hoYt2dgRcT_pj9KP1tgecLPwJHrLlUiTfNg0k5QHCSG-hw3RacUCX6ZH4ADrreFNcmuzj5tyvi4-nx_fdS7l_e37d3e9LzyhNJQjFleFagsROqk7kS00juUDKWcV0JQ3jlQaNquk0mqbiigITMs91XW34dXF3cn2YvxaMqZ1s1DiO4HBeYkuFqqTcMtHk6O05unQT9q0PdoJwbP8fx38B17pshw</recordid><startdate>201312</startdate><enddate>201312</enddate><creator>Knudsen, Søren Tang</creator><creator>Mosbech, Thomas Hammershaimb</creator><creator>Hansen, Birtha</creator><creator>Kønig, Else</creator><creator>Johnsen, Peter Christian</creator><creator>Kamper, Anne-Lise</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201312</creationdate><title>Difficulties in reaching therapeutic goals for hypertension and dysplipidaemia in patients with type 2 diabetes in general practice</title><author>Knudsen, Søren Tang ; 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Angiotensin-converting enzyme inhibitors (ACEI) or angiotensin II-receptor blockers (ARB) are recommended as primary antihypertensive therapy (AHT). To which extent these targets are met in Danish primary care is unknown.
This study was based on data from 2,057 patients with T2DM who were randomly selected from 64 general practitioners (GPs) from different regions of Denmark. Data were collected from the GPs' electronic records.
The mean age ± standard deviation was 66.2 ± 11.6 years; 58.7% were male. The mean systolic BP ± standard deviation was 132.6 ± 14.6 mmHg and the mean diastolic BP ± standard deviation was 78.1 ± 9.0 mmHg. 47.7% of the patients met the BP target. 79.5% of the patients were on AHT. 55.1% of the untreated and 46.0% of the treated patients met the BP target. 83.4% of the treated patients received ACEI or ARB. The median LDL was 2.2 (1.7-2.7) mmol/l. 63.7% of the patients met the LDL target. 73.7% of the patients received lipid-lowering therapy. 32.8% of the untreated and 74.4% of the treated patients met the LDL target.
AHT including ACEI and ARB and lipid-lowering therapy are widely used in T2DM in Danish primary care, but only half of the patients are at target for BP and two thirds are at target for LDL. Increased use of diuretics may improve BP control.
This study was funded by a grant from Boehringer Ingelheim, Denmark. The grant covered costs related to data collection, time spent by the general practitioners and data analysis by the DTU.
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| subjects | Aged Angiotensin Receptor Antagonists - therapeutic use Angiotensin-Converting Enzyme Inhibitors - therapeutic use Antihypertensive Agents - therapeutic use Blood Pressure Cholesterol, LDL - blood Denmark Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Female General Practice Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypercholesterolemia - blood Hypercholesterolemia - complications Hypercholesterolemia - drug therapy Hypertension - complications Hypertension - drug therapy Hypertension - physiopathology Hypoglycemic Agents - therapeutic use Hypolipidemic Agents - therapeutic use Male Middle Aged Patient Care Planning Practice Guidelines as Topic Treatment Outcome |
| title | Difficulties in reaching therapeutic goals for hypertension and dysplipidaemia in patients with type 2 diabetes in general practice |
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