The pharmacokinetics of methocarbamol and guaifenesin after single intravenous and multiple-dose oral administration of methocarbamol in the horse

A simple LC/MSMS method has been developed and fully validated to determine concentrations and characterize the concentration vs. time course of methocarbamol (MCBL) and guaifenesin (GGE) in plasma after a single intravenous dose and multiple oral dose administrations of MCBL to conditioned Thorough...

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Veröffentlicht in:	Journal of veterinary pharmacology and therapeutics 2014-02, Vol.37 (1), p.25-34
Hauptverfasser:	Rumpler, M. J., Colahan, P., Sams, R. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Drug Administration Schedule Expectorants - administration & dosage Expectorants - pharmacokinetics Female Guaifenesin - administration & dosage Guaifenesin - pharmacokinetics Horses - blood Horses - metabolism Injections, Intravenous - veterinary Male Methocarbamol - administration & dosage Methocarbamol - blood Methocarbamol - pharmacokinetics Muscle Relaxants, Central - administration & dosage Muscle Relaxants, Central - blood Muscle Relaxants, Central - pharmacokinetics
Online-Zugang:	Volltext
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