Advanced multiplicity adjustment methods in clinical trials

During the last decade, many novel approaches for addressing multiplicity problems arising in clinical trials have been introduced in the literature. These approaches provide great flexibility in addressing given clinical trial objectives and yet maintain strong control of the familywise error rate....

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Veröffentlicht in:	Statistics in medicine 2014-02, Vol.33 (4), p.693-713
Hauptverfasser:	Alosh, Mohamed, Bretz, Frank, Huque, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	adaptive alpha Algorithms Clinical trials Clinical Trials as Topic - methods Data Interpretation, Statistical Error analysis gatekeeping graphical methods Humans Medical statistics multiple testing α-propagation
Online-Zugang:	Volltext
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