Capsaicin 8% patch for treprostinil subcutaneous infusion site pain in pulmonary hypertension patients

Treprostinil sodium improves haemodynamics and symptoms in pulmonary arterial hypertension (PAH) patients, but its subcutaneous (s.c.) administration can produce severe local site pain, and lead to discontinuation of vital treatment. Treprostinil is a prostacyclin analogue which stimulates prostacyc...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2014-02, Vol.112 (2), p.337-347
Hauptverfasser:	Libri, V., Gibbs, J.S.R., Pinato, D.J., Iddamalgoda, T., Khengar, R.H., Gin-Sing, W., Huson, L., Anand, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antihypertensive Agents - adverse effects Antihypertensive Agents - therapeutic use Capsaicin - administration & dosage Capsaicin - therapeutic use capsaicin 8 clinical trial Double-Blind Method Epoprostenol - adverse effects Epoprostenol - analogs & derivatives Epoprostenol - therapeutic use Female Humans Hypertension, Pulmonary - drug therapy Infusions, Subcutaneous London Male Middle Aged pain Pain - chemically induced Pain - drug therapy pulmonary arterial hypertension Sensory System Agents - administration & dosage Sensory System Agents - therapeutic use Transdermal Patch Treatment Outcome treprostinil
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