Peniciketals A–C, New Spiroketals from Saline Soil Derived Penicillium raistrichii

Peniciketals A–C (1–3), three new spiroketals with a benzo-fused 2,8-dioxabicyclo[3.3.1]nonane moiety, were isolated from the saline soil derived fungus Penicillium raistrichii. Their structures including absolute configurations were established by NMR, X-ray diffraction, and ECD calculations. Thei...

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Veröffentlicht in:	Organic letters 2014-01, Vol.16 (1), p.90-93
Hauptverfasser:	Liu, Wei-Zhong, Ma, Li-Ying, Liu, De-Sheng, Huang, Yu-Ling, Wang, Chun-Hua, Shi, Shou-Sen, Pan, Xiao-Hong, Song, Xiao-Dong, Zhu, Rong-Xiu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemistry Antineoplastic Agents - isolation & purification Antineoplastic Agents - pharmacology Cell Line, Tumor Cell Proliferation - drug effects Dose-Response Relationship, Drug Drug Screening Assays, Antitumor HL-60 Cells Humans K562 Cells Models, Molecular Molecular Conformation Penicillium - chemistry Pyrans - chemistry Pyrans - isolation & purification Pyrans - pharmacology Quantum Theory Salinity Soil - chemistry Spiro Compounds - chemistry Spiro Compounds - isolation & purification Spiro Compounds - pharmacology Stereoisomerism Structure-Activity Relationship
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